Clinical Trials Dashboard

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Chart showing the number clinical trials by phase initiated in 2024
Number of clinical trials by phase initiated in 2024

Studies Ending October-November

Jiangsu Yahong Meditech Co., Ltd aka Asieris

A Phase 1b Study to Evaluate APL-1401 in Patients With Moderately to Severely Active Ulcerative Colitis
Completion: Apr 30, 2025
Phase 1 NCT05743010
Ulcerative Colitis

Johnpro Biotech, Inc.

Phase II/III Trial of CCRT With or Without JP001 for Newly Diagnosed GBM
Completion: Apr 30, 2025
Phase 2 / Phase 3 NCT03008148
Glioblastoma

Cellevolve Bio Inc

A Phase 2 Study Evaluating JCPyV-specific T Cell Therapy for PML
Completion: Apr 30, 2025
Phase 2 NCT05541549
Progressive Multifocal Leukoencephalopathy

Clinical Trial Selection

Trial InfoStatus and TimelineType and TreatmentCondition
Pancreatic Cancer Molecular Sub-classification Using Endoscopic Ultrasound Tissue Core Biopsy Samples
Medtronic
Phase not applicable
Past estimated: Jun 2, 2024
No interventions listed
Pancreas Cancer
Post Market Surveillance of the HeartMate 3 Left Ventricular Assist System in Korea
Abbott Medical Devices
Phase not applicable
Completed Jun 2, 2024
INTERVENTIONAL
  • HeartMate 3™ left ventricular assist system (HM3 LVAS)
Advanced Heart Failure
Prizvalve® Transcatheter Valve-in-Valve Implantation Exploratory Study
Shanghai NewMed Medical Co., Ltd.
Phase not applicable
Past estimated: Jun 2, 2024
INTERVENTIONAL
  • Prizvalve® system
Failing Bioprosthetic Valve
Study of Intramuscular Injections of ABBV-950 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Upper Limb Spasticity
Phase 1
Completed Jun 2, 2024
INTERVENTIONAL
  • ABBV-950
  • BOTOX
  • Placebo for ABBV-950
Upper Limb Spasticity
Study to Assess the Effect of AZD9291 on the Blood Levels of Simvastatin in Patients With EGFRm+ NSCLC
AstraZeneca
Phase 1
Completed Jun 3, 2024
INTERVENTIONAL
  • AZD9291 tablet dosing
  • Pharmacokinetic sampling - AZ5140 and AZ7550
  • Pharmacokinetic sampling - AZD9291
  • Pharmacokinetic sampling - simvastatin
  • Simvastatin
Non Small Cell Lung Cancer
A Study to Evaluate 3 Dose Schedules of Daratumumab in Participants With Smoldering Multiple Myeloma
Janssen Research & Development, LLC
Phase 2
Completed Jun 3, 2024
INTERVENTIONAL
  • daratumumab
Multiple Myeloma
Study of ACY-241 Alone and in Combination With Pomalidomide and Dexamethasone in Multiple Myeloma
Celgene
Phase 1
Completed Jun 3, 2024
INTERVENTIONAL
  • ACY-241
  • Dexamethasone
  • Pomalidomide
Multiple Myeloma
Phase III Study of Nazartinib (EGF816) Versus Erlotinib/Gefitinib in First-line Locally Advanced / Metastatic NSCLC With EGFR Activating Mutations
Novartis Pharmaceuticals
Phase 3
Past estimated: Jun 3, 2024
INTERVENTIONAL
  • EFG816
  • erlotinib or gefitinib
Carcinoma, Non-small Cell Lung
Effectiveness, Safety, Adherence, and Health-related Quality of Life in HIV-1 Infected Adults Receiving Bictegravir/ Emtricitabine/Tenofovir Alafenamide
Gilead Sciences
Phase not applicable
Completed Jun 3, 2024
OBSERVATIONAL
  • B/F/TAF
HIV-1-infection
VT-EBV-N for Treatment of Severe in EBV Positive Extranodal NK/T Cell Lymphoma Patients
ViGenCell Inc.
Recruiting Phase 2
Past estimated: Jun 3, 2024
INTERVENTIONAL
  • Placebo
  • VT-EBV-N
Extranodal NK/T-cell Lymphoma
Serum Neutrophil Gelatinase-associated Lipocalins (NGAL) and Chronic Kidney Disease
BioPorto Diagnostics
Phase not applicable
Completed Jun 3, 2024
No interventions listed
AKI Acute Kidney Injury CKD Chronic Kidney Diseases Emergency Department NGAL Neutrophil Gelatinase-associated Lipocalin
CNS Penetration, PK and PD of Preoperative CC-90010 in Progressive/Recurrent Diffuse Astrocytoma, Anaplastic Astrocytoma and Glioblastoma
Celgene
Phase 1
Completed Jun 3, 2024
INTERVENTIONAL
  • CC-90010
Astrocytoma Glioblastoma
Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia (NL003-CLI-III-1)
Beijing Northland Biotech. Co., Ltd.
Phase 3
Completed Jun 3, 2024
INTERVENTIONAL
  • NL003
  • Normal Saline
Arterial Occlusive Disease Ischemia Peripheral Vascular Disease Ulcers
A Study to Investigate the Efficacy and Safety of Atezolizumab (Tecentriq) in Previously-Treated Patients With Advanced Thymic Carcinoma
Hoffmann-La Roche
Phase 2
Completed Jun 3, 2024
INTERVENTIONAL
  • Atezolizumab
Carcinoma, Thymic
In Vitro Study of the Biological and Immunological Activity of Imotopes® Candidates on Blood Cells of Patients With Stabilized NMO
Imcyse SA
Phase not applicable
Completed Jun 3, 2024
INTERVENTIONAL
  • Blood sampling
Neuromyelitis Optica
Sym021 in Combination With Either Sym022 or Sym023 or Sym023 and Irinotecan in Patients With Recurrent Advanced Selected Solid Tumor Malignancies
Symphogen A/S
Phase 1
Completed Jun 3, 2024
INTERVENTIONAL
  • Irinotecan Hydrochloride
  • Sym021
  • Sym022
  • Sym023
Metastatic Cancer Solid Tumor
HBM4003 Combine With Toripalimab in Patients With Advanced NEN and Other Solid Tumors Study
Harbour BioMed (Guangzhou) Co. Ltd.
Not yet recruiting Phase 1
Past estimated: Jun 3, 2024
INTERVENTIONAL
  • HBM4003
  • Toripalimab
Solid Tumors
REINVENT Registry (Registry of the Nerve Gap Repair From Integra)
Integra LifeSciences Corporation
Phase not applicable
Completed Jun 3, 2024
OBSERVATIONAL
  • NeuraGen
  • NeuraGen 3D
Peripheral Nerve Injuries
A Study to Evaluate Safety and Efficacy of AMB-05X Injections in Subjects With TGCT
AmMax Bio, Inc.
Phase 2
Completed Jun 3, 2024
INTERVENTIONAL
  • AMB-05X
Pigmented Villonodular Synovitis TGCT Tenosynovial Giant Cell Tumor
SMART Stimulation: Precision Neuromodulation of Cognition in Older Adults
Soterix Medical
Phase not applicable
Completed Jun 3, 2024
INTERVENTIONAL
  • cognitive training
  • tDCS
Aging
A Research Study to Understand How Oral Semaglutide Works in People With Type 2 Diabetes in India
Novo Nordisk A/S
Phase not applicable
Completed Jun 3, 2024
OBSERVATIONAL
  • Oral semaglutide
Diabetes Mellitus, Type 2
AI-09 In Subjects With Glabellar Lines, GL-101
Eirion Therapeutics Inc.
Phase 1 / Phase 2
Completed Jun 3, 2024
INTERVENTIONAL
  • AI-09
  • Vehicle
Glabellar Frown Lines
A Study to Assess NEU-411 in Healthy Participants
Neuron23 Inc.
Phase 1
Completed Jun 3, 2024
INTERVENTIONAL
  • NEU-411
  • Placebo
Healthy
Post Market Observational Retrospective Study of Glycar Bovine Pericardial Patch (CIP-003)
GLYCAR SA (Pty) Ltd
Phase not applicable
Completed Jun 3, 2024
OBSERVATIONAL
  • Glycar Pericardial Patch
Cardiac Anomaly Cardiac Defect Pericardial Defect
A Study to Investigate the Relative Bioavailability and Food Effect of an Oral Capsid Inhibitor Tablet Formulation Compared With Other Oral Tablet Formulations in Male and Female Healthy Participants
ViiV Healthcare
Phase 1
Completed Jun 3, 2024
INTERVENTIONAL
  • VH4004280 Formulation A
  • VH4004280 Formulation B
  • VH4004280 Formulation C
  • VH4004280 Formulation D
  • VH4004280 Formulation E
HIV Infections
Personalized Management of Type 2 Diabetes Using AI-Guided (GenAIS TM) Dietary Supplementation
Triangel Scientific
Phase not applicable
Completed Jun 3, 2024
INTERVENTIONAL
  • The AI-guided practice dietary supplements group
  • The standard practice dietary supplements intervention
Diabetes
A Single Group Study to Evaluate the Effects of a pH Balanced Cleanser on Women's Intimate Health.
Citruslabs
Phase not applicable
Completed Jun 3, 2024
INTERVENTIONAL
  • pH Balanced Cleanser
Vaginal Health Vaginal pH
A Single Group Study to Evaluate the Effects of a pH Balanced Cleanser on Women's Intimate Health.
Love Wellness
Phase not applicable
Completed Jun 3, 2024
INTERVENTIONAL
  • pH Balanced Cleanser
Vaginal Health Vaginal pH
Multistrain Probiotics Against Bacterial Vaginosis
Institut AllergoSan Pharma GmbH
Phase 1
Completed Jun 3, 2024
INTERVENTIONAL
  • OMNi-BiOTiC® FLORA plus+
  • antibiotic
Bacterial Vaginosis (BV)
Efficacy and Safety Study of First-line Treatment With Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Women With Persistent, Recurrent, or Metastatic Cervical Cancer (MK-3475-826/KEYNOTE-826)
Merck Sharp & Dohme LLC
Phase 3
Completed Jun 4, 2024
INTERVENTIONAL
  • Bevacizumab
  • Carboplatin
  • Cisplatin
  • Paclitaxel
  • Pembrolizumab
  • Placebo to pembrolizumab
Cervical Cancer
Study of STRO-002, an Anti-Folate Receptor Alpha (FolRα) Antibody Drug Conjugate in Ovarian & Endometrial Cancers
Sutro Biopharma, Inc.
Phase 1
Completed Jun 4, 2024
INTERVENTIONAL
  • STRO-002
Endometrial Cancer Endometrioid Adenocarcinoma Fallopian Tube Cancer Ovarian Cancer Ovarian Carcinoma Ovary Cancer Primary Peritoneal Carcinoma
Study of Safety and Efficacy of CFZ533 in Type 1 Diabetes Pediatric and Young Adult Subjects
Novartis Pharmaceuticals
Phase 2
Completed Jun 4, 2024
INTERVENTIONAL
  • CFZ533
  • Placebo
Type 1 Diabetes Mellitus
A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus
UCB Biopharma SRL
Phase 3
Completed Jun 4, 2024
INTERVENTIONAL
  • DZP
  • Placebo
Systemic Lupus Erythematosus
Non-comparative Study of IFX-1 Alone or IFX-1+Pembrolizumab in Patients With Locally Advanced or Metastatic cSCC.
InflaRx GmbH
Phase 2
Completed Jun 4, 2024
INTERVENTIONAL
  • Vilobelimab
  • Vilobelimab + pembrolizumab combination therapy
SCC - Squamous Cell Carcinoma of Skin
Non-comparative Study of IFX-1 Alone or IFX-1+Pembrolizumab in Patients With Locally Advanced or Metastatic cSCC.
Merck Sharp & Dohme LLC
Phase 2
Completed Jun 4, 2024
INTERVENTIONAL
  • Vilobelimab
  • Vilobelimab + pembrolizumab combination therapy
SCC - Squamous Cell Carcinoma of Skin
Safety and Efficacy of Allogeneic NK Cell Infusions in Patients With Relapsed/Refractory AML and High Risk MDS
Coeptis Therapeutics
Phase 1
Completed Jun 4, 2024
INTERVENTIONAL
  • DVX201
AML, Adult Recurrent MDS
Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Neurotrophic Keratitis Subjects
Claris Biotherapeutics, Inc.
Phase 1 / Phase 2
Completed Jun 4, 2024
INTERVENTIONAL
  • CSB-001 Ophthalmic Solution 0.1%
  • Vehicle Control
Neurotrophic Keratitis
A Randomized Controlled Trial of InterVapor® in France - the TARGET Trial
Uptake Medical Technology, Inc.
Phase not applicable
Completed Jun 4, 2024
INTERVENTIONAL
  • Optimal Medical Therapy
  • Treatment plus Optimal Medical Therapy
Emphysema
A Clinical Trial to Investigate the Safety and Tolerability, Efficacy, Pharmacokinetics, Pharmacodynamics and Immunogenicity of 2 Dose Regimens of ARGX-117 in Adults with Multifocal Motor Neuropathy
Phase 2
Completed Jun 4, 2024
INTERVENTIONAL
  • ARGX-117
  • Placebo
Multifocal Motor Neuropathy
Placebo-controlled, Proof-of-concept Study to Evaluate the Safety and Efficacy of Lanifibranor Alone and in Combination With SGLT2 Inhibitor EmpaGliflozin in patiEnts With NASH and Type 2 Diabetes Mellitus
Inventiva Pharma
Phase 2
Completed Jun 4, 2024
INTERVENTIONAL
  • Empagliflozin
  • IVA337
  • Placebo
Diabetes Mellitus, Type 2 NASH - Nonalcoholic Steatohepatitis
A Phase 2a Study to Investigate REM0046127 in Mild to Moderate Alzheimer's Disease
Phase 2
Completed Jun 4, 2024
INTERVENTIONAL
  • Placebo
  • REM0046127 High Dose
  • REM0046127 Low Dose
Alzheimer Disease
A Phase 3 Study of Recombinant Anti-IL-17A Humanized Monoclonal Antibody in Chinese Participants with Moderate-to-Severe Plaque Psoriasis
Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.
Phase 3
Completed Jun 4, 2024
INTERVENTIONAL
  • 608 Q2W
  • 608 Q4W
  • Placebo
Psoriasis
A Study of Modakafusp Alfa in Adult Participants With Multiple Myeloma
Phase 1
Completed Jun 4, 2024
INTERVENTIONAL
  • Bortezomib
  • Carfilzomib
  • Daratumumab
  • Lenalidomide
  • Modakafusp alfa
  • Pomalidomide
Multiple Myeloma
Thumb Hemi-Arthroplasty With Natural Kinematics (THANKS) Trial
Loci Orthopaedics
Phase not applicable
Completed Jun 4, 2024
INTERVENTIONAL
  • InDx Implant for the carpometacarpal joint
Osteoarthritis Thumb Base Joint
Harnessing Allo-immunity to Enhance Immune Checkpoint Inhibitor Responses in Advanced NSCLC
Oncovir, Inc.
Phase 1 / Phase 2
Completed Jun 4, 2024
INTERVENTIONAL
  • IVIG
  • Poly ICLC
Stage IV NSCLC
A Study Assessing the Mass Balance, Pharmacokinetics, and Metabolite Profiles of a Single Oral Dose of [14C]INCB099280 in Healthy Male Participants
Incyte Corporation
Phase 1
Completed Jun 4, 2024
INTERVENTIONAL
  • INCB099280
Healthy Participants
A Study to Assess the Bioequivalence Between Brivaracetam Tablet and Dry Syrup in Healthy Japanese Male Study Participants
UCB Biopharma SRL
Phase 1
Completed Jun 4, 2024
INTERVENTIONAL
  • brivaracetam (BRV) dry syrup
  • brivaracetam (BRV) tablet
Healthy Study Participants
A Clinical Study to Evaluate the Tolerance, Pharmacokinetics and Efficacy of TQ-A3334 Tablets
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Phase 1 / Phase 2
Completed Jun 4, 2024
INTERVENTIONAL
  • TQ-A3334 tablets
  • TQ-A3334 tablets + Anlotinib capsules
Non Small Cell Lung Cancer
Clinical Trial of Wrist Ambulatory Blood Pressure Monitor in Conformance With the EN ISO 81060-2:2018+AMD1:2020
Huawei Device Co., Ltd
Phase not applicable
Completed Jun 4, 2024
INTERVENTIONAL
  • Wrist Ambulatory Blood Pressure Monitor
Blood Pressure
A Study of Enlicitide Decanoate (MK-0616), Warfarin, and Lisinopril in Healthy Adult Participants (MK-0616-026)
Merck Sharp & Dohme LLC
Phase 1
Completed Jun 4, 2024
INTERVENTIONAL
  • Enlicitide Decanoate
  • Lisinopril
  • Warfarin
Healthy
A Phase 2 Study to Evaluate Safety of Long-term AL001 Dosing in Frontotemporal Dementia (FTD) Patients (INFRONT-2)
Alector Inc.
Phase 2
Completed Jun 5, 2024
INTERVENTIONAL
  • AL001
Frontotemporal Dementia
A Phase 2 Study to Evaluate Safety of Long-term AL001 Dosing in Frontotemporal Dementia (FTD) Patients (INFRONT-2)
GlaxoSmithKline
Phase 2
Completed Jun 5, 2024
INTERVENTIONAL
  • AL001
Frontotemporal Dementia
SEMA4D Blockade Safety and Brain Metabolic Activity in Alzheimer's Disease (AD)
Vaccinex Inc.
Phase 1 / Phase 2
Completed Jun 5, 2024
INTERVENTIONAL
  • Pepinemab
  • Placebo
Alzheimer Disease
A Study of Mirikizumab (LY3074828) in Participants With Ulcerative Colitis
Eli Lilly and Company
Phase 3
Past estimated: Jun 5, 2024
INTERVENTIONAL
  • Mirikizumab IV
  • Mirikizumab SC
  • Placebo IV
  • Placebo SC
  • Vedolizumab IV
Ulcerative Colitis
Sweet Tooth: Nature or Nurture? Role of Long-term Dietary Sweetness Exposure on Sweetness Preferences
Arla Foods
Phase not applicable
Completed Jun 5, 2024
INTERVENTIONAL
  • Dietary intervention
Food Preferences
Sweet Tooth: Nature or Nurture? Role of Long-term Dietary Sweetness Exposure on Sweetness Preferences
Cargill
Phase not applicable
Completed Jun 5, 2024
INTERVENTIONAL
  • Dietary intervention
Food Preferences
Sweet Tooth: Nature or Nurture? Role of Long-term Dietary Sweetness Exposure on Sweetness Preferences
Unilever R&D
Phase not applicable
Completed Jun 5, 2024
INTERVENTIONAL
  • Dietary intervention
Food Preferences
Study of Irinotecan Liposome Injection in Patients With Advanced Breast Cance
CSPC Ouyi Pharmaceutical Co., Ltd.
Phase 1
Completed Jun 5, 2024
INTERVENTIONAL
  • Irinotecan Liposome Injection
Advanced Breast Cancer
A Study to Determine the Safety, Pharmacokinetics, and Pharmacodynamics of DNL343 in Participants With Amyotrophic Lateral Sclerosis
Denali Therapeutics Inc.
Phase 1
Completed Jun 5, 2024
INTERVENTIONAL
  • DNL343
  • Placebo
Amyotrophic Lateral Sclerosis
Study of the Effectiveness and Safety of SHR-1314 for Psoriatic Arthritis
Suzhou Suncadia Biopharmaceuticals Co., Ltd.
Phase 2
Completed Jun 5, 2024
INTERVENTIONAL
  • SHR-1314 injection
  • placebo
Psoriatic Arthritis
Survey Among Healthcare Professionals Treating Patients With Metastatic Breast Cancer in Selected European Countries to Evaluate Their Knowledge on Management of Hyperglycemia When Using Alpelisib
Novartis Pharmaceuticals
Phase not applicable
Completed Jun 5, 2024
OBSERVATIONAL
  • Piqray Prescriber's/HCP guide for hyperglycemia
Breast Cancer
Assess Safety and Tolerability of ART-123 + FOLFOX + Bevacizumab in Metastatic Colorectal Cancer Patients
Veloxis Pharmaceuticals
Phase 1
Completed Jun 5, 2024
INTERVENTIONAL
  • Placebo
  • thrombomodulin alfa
Chemotherapy-induced Peripheral Neuropathy
A Trial to Assess Steviol Glycosides on Acute Appetite Hormone Release
Cargill
Phase not applicable
Completed Jun 5, 2024
INTERVENTIONAL
  • Glucose
  • Rebaudioside A
  • Steviol Glycosides
  • Steviol Glycosides plus glucose
  • Water
Overweight and Obesity Type 2 Diabetes Mellitus
A Study of Nanrilkefusp Alfa (SOT101) in Combination With Cetuximab to Evaluate the Efficacy and Safety in Patients With Colorectal Cancer
SOTIO Biotech AG
Phase 2
Completed Jun 5, 2024
INTERVENTIONAL
  • Cetuximab
  • Nanrilkefusp alfa
Colorectal Cancer
Noninvasive Monitoring of Uterine Activity and Fetal Heart Rate
OB-Tools Ltd.
Phase not applicable
Completed Jun 5, 2024
OBSERVATIONAL
  • TrueLabor
Fetal Heart Rate or Rhythm Abnormality Affecting Newborn During Labor Obstetric Complication Uterine Contractions
Study of Two Digital Therapeutics for the Prevention of Episodic Migraine Receiving CGRP Therapy (ReMMiD-C)
Click Therapeutics, Inc.
Phase 3
Completed Jun 5, 2024
INTERVENTIONAL
  • Click Digital Therapeutic
Episodic Migraine Headache Headache, Migraine Migraine
A Study in Healthy People to Test Whether Iclepertin Has an Effect on Cardiac Safety
Boehringer Ingelheim
Phase 1
Completed Jun 5, 2024
INTERVENTIONAL
  • Iclepertin
  • Iclepertin Placebo
  • Moxifloxacin
  • Moxifloxacin Placebo
Healthy
A Retrospective Observational Study of Ustekinumab Among Bio-naive Participants With Crohn's Disease in China
Xian-Janssen Pharmaceutical Ltd.
Phase not applicable
Completed Jun 5, 2024
OBSERVATIONAL
  • Ustekinumab
Crohn Disease
A Study to Evaluate Efficacy of EB-PA as Protein Amplifier for Skeletal Muscle Strength & Growth
Vedic Lifesciences Pvt. Ltd.
Phase not applicable
Past estimated: Jun 5, 2024
INTERVENTIONAL
  • Resistance Training + Placebo (Capsule) + Placebo (Sachet)
  • Resistance Training + Whey protein (40 gms) + EB-PA (500 mg)
  • Resistance Training + Whey protein (40 gms) + Placebo (Capsule)
Skeletal Muscle Strength & Growth
A Study of GZR18 Injection in Obese/Overweight Patients
Gan and Lee Pharmaceuticals, USA
Phase 2
Completed Jun 5, 2024
INTERVENTIONAL
  • GZR18
  • Placebo
Obesity Overweight
The COAT Trial: Cequa's Onset of Action Trial
Research Insight LLC
Phase 4
Completed Jun 5, 2024
INTERVENTIONAL
  • Cyclosporine ophthalmic solution
Dry Eye
Efficacy Study of Nivolumab Plus Ipilimumab or Nivolumab Plus Chemotherapy Against Chemotherapy in Stomach Cancer or Stomach/Esophagus Junction Cancer
Bristol-Myers Squibb
Phase 3
Completed Jun 6, 2024
INTERVENTIONAL
  • Capecitabine
  • Fluorouracil
  • Ipilimumab
  • Leucovorin
  • Nivolumab
  • Oxaliplatin
Esophageal Adenocarcinoma Gastric Cancer Gastroesophageal Junction Cancer
Efficacy Study of Nivolumab Plus Ipilimumab or Nivolumab Plus Chemotherapy Against Chemotherapy in Stomach Cancer or Stomach/Esophagus Junction Cancer
Bristol-Myers Squibb
Phase 3
Completed Jun 6, 2024
INTERVENTIONAL
  • Capecitabine
  • Fluorouracil
  • Ipilimumab
  • Leucovorin
  • Nivolumab
  • Oxaliplatin
Esophageal Adenocarcinoma Gastric Cancer Gastroesophageal Junction Cancer
Efficacy Study of Nivolumab Plus Ipilimumab or Nivolumab Plus Chemotherapy Against Chemotherapy in Stomach Cancer or Stomach/Esophagus Junction Cancer
Ono Pharmaceutical Co. Ltd
Phase 3
Completed Jun 6, 2024
INTERVENTIONAL
  • Capecitabine
  • Fluorouracil
  • Ipilimumab
  • Leucovorin
  • Nivolumab
  • Oxaliplatin
Esophageal Adenocarcinoma Gastric Cancer Gastroesophageal Junction Cancer
Efficacy Study of Nivolumab Plus Ipilimumab or Nivolumab Plus Chemotherapy Against Chemotherapy in Stomach Cancer or Stomach/Esophagus Junction Cancer
Ono Pharmaceutical Co. Ltd
Phase 3
Completed Jun 6, 2024
INTERVENTIONAL
  • Capecitabine
  • Fluorouracil
  • Ipilimumab
  • Leucovorin
  • Nivolumab
  • Oxaliplatin
Esophageal Adenocarcinoma Gastric Cancer Gastroesophageal Junction Cancer
Post-Market Clinical Follow-up Study with ASPIREX®S to Assess the Safety and Effectiveness in the Treatment of DVT
Straub Medical AG
Phase not applicable
Completed Jun 6, 2024
No interventions listed
Bypass Complication Deep Vein Thrombosis Dialysis Shunt Stent Occlusion
PROSEEK: A Phase 2 Study In Early Parkinson's Disease Patients Evaluating The Safety And Efficacy Of Abl Tyrosine Kinase Inhibition Using K0706
Sun Pharma Advanced Research Company Limited
Phase 2
Completed Jun 6, 2024
INTERVENTIONAL
  • K0706
  • placebo
Early Parkinson Disease
Study to Learn More About the Safety and Effectiveness of Rivaroxaban (Xarelto) When Given Together With Acetylsalicylic Acid to Indian People With Narrowing of the Arteries of the Heart (CAD) and/or With Reduced Blood Flow in the Arteries of the Legs and Arms With Symptoms (Symptomatic PAD)
Phase not applicable
Completed Jun 6, 2024
OBSERVATIONAL
  • Acetylsalicylic acid(ASA)
  • Rivaroxaban (Xarelto,Bay 59-7939)
Coronary Artery Disease (CAD) Prevention of Atherothrombotic Events Symptomatic Peripheral Artery Disease (Symptomatic PAD)
A Study to Test the Safety, Pharmacokinetics, and Efficacy of UCB9741 in Healthy Study Participants and in Study Participants With Atopic Dermatitis
UCB Biopharma SRL
Phase 1 / Phase 2
Completed Jun 6, 2024
INTERVENTIONAL
  • Intravenous Placebo
  • Subcutaneous Placebo
  • UCB9741
Atopic Dermatitis
Efficacy and Safety of Lomitapide in Paediatric Patients With Homozygous Familial Hypercholesterolaemia (HoFH)
Amryt Pharma
Phase 3
Completed Jun 6, 2024
INTERVENTIONAL
  • Lomitapide
Homozygous Familial Hypercholesterolaemia (HoFH)
SER150 vs Placebo in Diabetic Kidney Disease
Serodus AS
Phase 2 / Phase 3
Completed Jun 6, 2024
INTERVENTIONAL
  • Placebo
  • SER150
Diabetic Kidney Disease
A Study to Assess the Safety and Efficacy of Inclacumab in Participants With Sickle Cell Disease Experiencing Vaso-occlusive Crises
Phase 3
Completed Jun 6, 2024
INTERVENTIONAL
  • Inclacumab
  • Placebo
Sickle Cell Disease Vaso-occlusive Crisis Vaso-occlusive Pain Episode in Sickle Cell Disease
A Clinical Trial Evaluating the Efficacy and Safety of HSK21542 in Patients with Chronic Kidney Disease-Associated Pruritus
Haisco Pharmaceutical Group Co., Ltd.
Phase 3
Completed Jun 6, 2024
INTERVENTIONAL
  • HSK21542
  • Placebo
Hemodialysis Patients with Moderate-to-Severe Pruritus Pruritus
Extended Treatment and Follow-up of Subjects Treated With Belumosudil in Study KD025-208 or Study KD025-213
Kadmon, a Sanofi Company
Phase 2
Completed Jun 6, 2024
INTERVENTIONAL
  • Belumosudil 200 mg BID
  • Belumosudil 200 mg QD
  • Belumosudil 400 mg QD
Chronic Graft-versus-host-disease
A Study to Test How Well Different Doses of BI 1815368 Are Tolerated by Healthy Men
Boehringer Ingelheim
Phase 1
Completed Jun 6, 2024
INTERVENTIONAL
  • BI 1815368
  • Matching placebo
Healthy
Evaluation of Home-based Sensor System to Detect Health Decompensation in Elderly Patients With History of CHF or COPD
Sensorum Health Inc.
Phase not applicable
Past estimated: Jun 6, 2024
OBSERVATIONAL
  • Data collection
CHF COPD COPD Exacerbation Chronic Obstructive Pulmonary Disease Congestive Heart Failure
Brazilian Reality in the Diagnosis and Treatment of Diffuse Large B Cell Lymphoma - BRA-DLBCL
AstraZeneca
Phase not applicable
Completed Jun 6, 2024
No interventions listed
Diffuse Large B Cell Lymphoma
Pilot Clinical Investigation to Evaluate a Prototype of Sensor Measuring Ventilator-derived Parameters
Archeon
Phase not applicable
Completed Jun 6, 2024
INTERVENTIONAL
  • prototype of sensor
Mechanically Ventilated Patients
A Clinical Study to Evaluate the Safety of CS-1103 in Healthy Participants
Clear Scientific, Inc.
Phase 1
Completed Jun 6, 2024
INTERVENTIONAL
  • CS-1103
  • Sterile Saline
Methamphetamine Abuse Methamphetamine Intoxication Substance Use Disorders
Xpert Hepatitis-C Virus (HCV) Test on the GeneXpert Xpress System
Cepheid
Phase not applicable
Completed Jun 6, 2024
OBSERVATIONAL
  • Xpert HCV
HCV
Allogeneic Hematopoietic Stem Cell Transplantation in Patients With Myelodysplastic Syndrome Low Risk
Neovii Biotech
Phase not applicable
Completed Jun 7, 2024
INTERVENTIONAL
  • transplantation
MDS
Allogeneic Hematopoietic Stem Cell Transplantation in Patients With Myelodysplastic Syndrome Low Risk
Novartis
Phase not applicable
Completed Jun 7, 2024
INTERVENTIONAL
  • transplantation
MDS
A Study of Pre-Operative Treatment With Cryoablation and Immune Therapy in Early Stage Breast Cancer
Bristol-Myers Squibb
Phase not applicable
Completed Jun 7, 2024
INTERVENTIONAL
  • Cryoablation
  • Ipilimumab
  • Nivolumab
Breast Cancer
A Study of INCB050465 in Relapsed or Refractory Follicular Lymphoma
Incyte Corporation
Phase 2
Completed Jun 7, 2024
INTERVENTIONAL
  • Parsaclisib
Lymphoma
Study of the Efficacy and Safety of HS-10234 in Patients With Chronic Hepatitis B Virus Infection
Jiangsu Hansoh Pharmaceutical Co., Ltd.
Phase 3
Completed Jun 7, 2024
INTERVENTIONAL
  • HS-10234
  • TDF
Chronic HBV Infection
Improving Neurological Health in Aging Via Neuroplasticity-based Computerized Exercise
Posit Science Corporation
Phase not applicable
Completed Jun 7, 2024
INTERVENTIONAL
  • Commercially available computerized training
  • Computerized Plasticity-Based Adaptive Cognitive Training
Healthy Aging
The MOOD Study - External Combined Occipital and Trigeminal Nerve Stimulation (eCOT-NS) for the Treatment of Major Depressive Disorder (MDD)
Neurolief Ltd.
Phase not applicable
Completed Jun 7, 2024
INTERVENTIONAL
  • Relivion®DP- Active
  • Relivion®DP- Sham
MDD
Effect of Tumor Treating Fields (TTFields, 150 KHz) Concomitant with Chemotherapy As First Line Treatment of Unresectable Gastroesophageal Junction or Gastric Adenocarcinoma
NovoCure Ltd.
Phase not applicable
Completed Jun 7, 2024
INTERVENTIONAL
  • Capecitabine
  • NovoTTF-100L(P)
  • Oxaliplatin
  • Trastuzumab
Gastric Cancer GastroEsophageal Cancer
Effect of Tumor Treating Fields (TTFields, 150 KHz) Concomitant with Chemotherapy As First Line Treatment of Unresectable Gastroesophageal Junction or Gastric Adenocarcinoma
Zai Lab (Shanghai) Co., Ltd.
Phase not applicable
Completed Jun 7, 2024
INTERVENTIONAL
  • Capecitabine
  • NovoTTF-100L(P)
  • Oxaliplatin
  • Trastuzumab
Gastric Cancer GastroEsophageal Cancer
Capivasertib+Fulvestrant vs Placebo+Fulvestrant as Treatment for Locally Advanced (Inoperable) or Metastatic HR+/HER2- Breast Cancer
AstraZeneca
Phase 3
Past estimated: Jun 7, 2024
INTERVENTIONAL
  • Capivasertib
  • Fulvestrant
  • Placebo
Locally Advanced (Inoperable) or Metastatic Breast Cancer
Amyloid Prediction in Early Stage Alzheimer's Disease From Acoustic and Linguistic Patterns of Speech - FUTURE Extension
Novoic Limited
Phase not applicable
Completed Jun 7, 2024
No interventions listed
Alzheimer Disease Alzheimer's Disease (Incl Subtypes) Mild Cognitive Impairment Preclinical Alzheimer's Disease Prodromal Alzheimer's Disease
A Study to Evaluate ELU001 in Patients With Solid Tumors That Overexpress Folate Receptor Alpha (FRα)
Elucida Oncology
Phase 1 / Phase 2
Completed Jun 7, 2024
INTERVENTIONAL
  • ELU001
Endometrial Adenocarcinoma Endometrial Cancer Endometrial Cancer Recurrent Endometrial Carcinosarcoma Endometrial Clear Cell Adenocarcinoma Endometrial Diseases Endometrial Neoplasms Endometrioid Adenocarcinoma Endometrioid Tumor Fallopian Tube Cancer Ovarian Adenocarcinoma Ovarian Cancer Ovarian Cancer Recurrent Ovarian Cancer Stage Ovarian Carcinoma Ovarian Diseases Ovarian Epithelial Cancer Ovarian Neoplasm Epithelial Ovarian Neoplasms Ovarian Serous Adenocarcinoma Ovary Cancer Ovary Disease Ovary Metastasis Ovary Neoplasm Peritoneal Cancer
Evaluation of Psilocybin (TRP-8802) in the Treatment of Binge Eating Disorder
TRYP Therapeutics
Phase 2
Completed Jun 7, 2024
INTERVENTIONAL
  • Psychotherapy
  • TRYP-0082
Binge Eating Disorder
Physician Acceptance of the NeuTrace System for Cardiac Electroanatomic Mapping
NeuTrace, Inc.
Recruiting Phase not applicable
Past estimated: Jun 7, 2024
INTERVENTIONAL
  • Electroanatomic mapping with the NeuTrace System
Arrhythmias, Cardiac Atrial Fibrillation Atrial Flutter
A Study to Test Whether BI 685509 Alone or in Combination With Empagliflozin Helps People With Liver Cirrhosis Caused by Viral Hepatitis or Non-alcoholic Steatohepatitis (NASH) Who Have High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver)
Boehringer Ingelheim
Phase 2
Completed Jun 7, 2024
INTERVENTIONAL
  • Avenciguat (BI 685509)
  • Empagliflozin
Hypertension, Portal Liver Diseases
A Study of HSK31858 in Participants with Non-Cystic Fibrosis Bronchiectasis
Haisco Pharmaceutical Group Co., Ltd.
Phase 2
Completed Jun 7, 2024
INTERVENTIONAL
  • HSK31858
  • placebo
Non-cystic Fibrosis Bronchiectasis (NCFBE)
ELU001 in Pediatric Subjects Who Have Relapsed and/or Refractory CBFA2T3-GLIS2-positive AML
Elucida Oncology
Phase 1
Completed Jun 7, 2024
INTERVENTIONAL
  • ELU001
AML, Childhood Acute Myeloid Leukemia Refractory Pediatric AML Relapsed Pediatric AML
A Study to Evaluate the Effects of Renal Function on Pharmacokinetics and Safety of DA-8010
Dong-A ST Co., Ltd.
Phase 1
Completed Jun 7, 2024
INTERVENTIONAL
  • DA-8010
Healthy Renal Impairment
Prospective Clinical Evaluation of BD NRFit™ Devices and Accessories.
Becton, Dickinson and Company
Phase not applicable
Completed Jun 7, 2024
OBSERVATIONAL
  • BD NRFit™ Spinal Needles, BD NRFit™ Spinal Introducer Needles, and BD NRFit™ Syringes
Analgesia Anesthesia
A Study to Evaluate the Safety and Immune Response of mRNA-1345, a Vaccine Targeting Respiratory Syncytial Virus (RSV), When Co-administered With a Fluzone HD, in Adults ≥65 Years of Age
ModernaTX, Inc.
Phase 3
Completed Jun 7, 2024
INTERVENTIONAL
  • Fluzone HD
  • Placebo
  • mRNA-1345
Respiratory Syncytial Virus
A Bioequivalence Study of Two Formulations of 10-mg Empagliflozin Tablets in Healthy Thai Volunteers Under Fasting Conditions
Pharma Nueva
Phase 1
Past estimated: Jun 7, 2024
INTERVENTIONAL
  • Empagliflozin 10 mg tablets
  • JARDIANCE®
Healthy Vollunteer
A Study to Evaluate the Drug Interaction Between Povorcitinib and the Oral Contraceptive Levonorgestrel/Ethinyl Estradiol in Healthy Adult Females
Incyte Corporation
Phase 1
Completed Jun 7, 2024
INTERVENTIONAL
  • Levonorgestrel/Ethinyl estradiol
  • Povorcitinib
Healthy Participants
Perceived Wellbeing and Focus with Daily Greens Supplementation
Gainful
Phase not applicable
Completed Jun 7, 2024
INTERVENTIONAL
  • Gainful Daily Performance Greens
Well-Being, Psychological
Post Authorization Safety Profile of Booster IndoVac COVID-19 Vaccination
PT Bio Farma
Phase not applicable
Completed Jun 7, 2024
No interventions listed
COVID-19
Post Marketing Surveillance on Safety Evaluation of POMALYST® (Pomalidomide) Treatment of Multiple Myeloma in Korea
Celgene
Phase not applicable
Past estimated: Jun 8, 2024
OBSERVATIONAL
  • POMALYST® (Pomalidomide)
Multiple Myeloma
Long-Term Extension Study With Eptinezumab as Preventive Treatment in Participants With Migraine in Japan
H. Lundbeck A/S
Phase 3
Completed Jun 8, 2024
INTERVENTIONAL
  • Eptinezumab
Migraine
Altropane Dose for Imaging Patients With Suspected Parkinson's Disease
Fortrea
Phase 2
Completed Jun 8, 2024
INTERVENTIONAL
  • Altropane (123I) Injection
Movement Disorders Parkinson Disease
Altropane Dose for Imaging Patients With Suspected Parkinson's Disease
GE Healthcare
Phase 2
Completed Jun 8, 2024
INTERVENTIONAL
  • Altropane (123I) Injection
Movement Disorders Parkinson Disease
A Six-Month Prospective Follow-Up Study of WB001
Woebot Health
Phase not applicable
Past estimated: Jun 8, 2024
OBSERVATIONAL
  • Observational
Postpartum Depression
Screening for Neonatal Jaundice With a Mobile Health Device: a Validation Study in Oaxaca, Mexico.
Picterus AS
Phase not applicable
Completed Jun 8, 2024
INTERVENTIONAL
  • Screening for neonatal jaundice with a mobile health device
Jaundice, Neonatal
Evaluation of the Know Your OQ™ Oral Health Literacy Tool in an Indian Population
Colgate Palmolive
Phase not applicable
Completed Jun 8, 2024
No interventions listed
Oral Health Literacy
Imaging-Guided Vessel Sizing in the Tibial Arteries
Abbott Medical Devices
Phase not applicable
Completed Jun 9, 2024
OBSERVATIONAL
  • Digital Subtraction Angiography
Critical Limb Ischemia Peripheral Artery Disease
Evaluate the Safety and Efficacy of Ferric Maltol Oral Suspension vs. Ferrous Sulfate Oral Liquid in Children and Adolescents Aged 2 to 17 Years With Iron-deficiency Anaemia, With a Single Arm Study in Infants Aged 1 Month to Less Than 2 Years
Shield Therapeutics
Phase 3
Completed Jun 9, 2024
INTERVENTIONAL
  • Ferric Maltol
  • Ferrous sulfate
Anemia Iron-deficiency
Smart Textile Sensor System for Health Monitoring
Nanowear Inc.
Phase not applicable
Past estimated: Jun 9, 2024
OBSERVATIONAL
  • Nanowear SimpleSense Wearable monitoring device
Blood Pressure Heart Disease Chronic Heart Rhythm Disorder Pulmonary Disease, Chronic Obstructive
A Study of Single and Multiple Oral Doses of TollB-001
Toll Biotech Co. Ltd. (Beijing)
Phase 1
Past estimated: Jun 9, 2024
INTERVENTIONAL
  • TollB-001 placebo
  • TollB-001 tablets
Rheumatoid Arthritis
A Study of Genolair in Two Dosage Forms (Solution and Lyophilisate) and Xolair® in Healthy Volunteers
AO GENERIUM
Phase 1
Completed Jun 9, 2024
INTERVENTIONAL
  • Genolair, lyophilisate for the preparation of solution for subcutaneous administration
  • Genolair, solution for subcutaneous administration, 150 mg
  • Xolair®, solution for subcutaneous administration, 150 mg
Allergic Asthma
HORIZON: A Phase II Study to Evaluate the Safety and Efficacy of Two Doses of GT005
Gyroscope Therapeutics Limited
Phase 2
Completed Jun 10, 2024
INTERVENTIONAL
  • GT005: High Dose
  • GT005: Medium Dose
Dry Age-related Macular Degeneration
HORIZON: A Phase II Study to Evaluate the Safety and Efficacy of Two Doses of GT005
Novartis Pharmaceuticals
Phase 2
Completed Jun 10, 2024
INTERVENTIONAL
  • GT005: High Dose
  • GT005: Medium Dose
Dry Age-related Macular Degeneration
Romosozumab in Women With Chronic SCI
Phase 2
Completed Jun 10, 2024
INTERVENTIONAL
  • Alendronate
  • Romosozumab
Bone Loss Chronic Spinal Paralysis Osteopenia, Osteoporosis Osteoporosis Spinal Cord Injuries
A Study to Evaluate DAY101 in Pediatric and Young Adult Patients With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors
Day One Biopharmaceuticals, Inc.
Phase 2
Past estimated: Jun 10, 2024
INTERVENTIONAL
  • DAY101
Advanced Solid Tumor Low-grade Glioma
Phase 1 Safety and Tolerability Study of MSK-DA01 Cell Therapy for Advanced Parkinson's Disease
BlueRock Therapeutics
Phase 1
Completed Jun 10, 2024
INTERVENTIONAL
  • MSK-DA01
  • MSK-DA01 Cell Delivery Device
Advanced Parkinson's Disease
Bridge to HOPE: Hypothermic Oxygenated Perfusion Versus Cold Storage Prior to Liver Transplantation
Bridge to Life Ltd.
Phase not applicable
Completed Jun 10, 2024
INTERVENTIONAL
  • Static cold storage
  • VitaSmart Liver Machine Perfusion System
End Stage Liver DIsease Liver Failure
A Study to Assess Change in Disease Activity and Adverse Events of Adalimumab in Chinese Participants Requiring High Dose Corticosteroids for Active Non-Infectious Intermediate, Posterior, or Pan-Uveitis
Phase 4
Completed Jun 10, 2024
INTERVENTIONAL
  • Adalimumab
Non-infectious Intermediate Posterior- or Pan-uveitis
Study to Evaluate the Safety, Tolerability, and PK of Pacritinib
CTI BioPharma
Phase 1
Completed Jun 10, 2024
INTERVENTIONAL
  • oral dose of 200 mg pacritinib twice daily (BID)
Hepatic Impairment
Study to Evaluate the Safety, Tolerability, and PK of Pacritinib
PPD DEVELOPMENT, LP
Phase 1
Completed Jun 10, 2024
INTERVENTIONAL
  • oral dose of 200 mg pacritinib twice daily (BID)
Hepatic Impairment
A Study of Safety and Drug Levels of HIB210 in Healthy Volunteers
HI-Bio, A Biogen Company
Phase 1
Completed Jun 10, 2024
INTERVENTIONAL
  • HIB210
  • Placebo
Autoimmunity Immune System Diseases
Retrospective Medical Chart Review Study to Describe the Experience of SLE Patients Treated With Anifrolumab in the Early Access Programs.
AstraZeneca
Phase not applicable
Completed Jun 10, 2024
OBSERVATIONAL
  • None (Observational study)
Systemic Lupus Erythematosus
A Study to Test How Either a Capsule or a Tablet With NDec (Decitabine and Tetrahydrouridine) Works in the Body of Healthy People
Novo Nordisk A/S
Phase 1
Completed Jun 10, 2024
INTERVENTIONAL
  • Decitabine-THU
Healthy Volunteers
A Study to Learn About How BAY2927088 Affects the Level of Dabigatran or Rosuvastatin in the Blood When These Drugs Are Taken Together in Healthy Participants
Phase 1
Completed Jun 10, 2024
INTERVENTIONAL
  • BAY2927088
  • Dabigatran etexilate
  • Rosuvastatin
Advanced Non-small Cell Lung Cancer EGFR Mutation HER2 Mutation Healthy Volunteers
A Study to Evaluate the Pharmacokinetics and Safety Between HCP2303 and Co-administration of Each Component in Healthy Volunteers
Hanmi Pharmaceutical Company Limited
Phase 1
Completed Jun 10, 2024
INTERVENTIONAL
  • HCP2303
  • RLD2102
  • RLD2302
Healthy
Tandem Freedom - Feasibility Trial 1
Tandem Diabetes Care, Inc.
Phase not applicable
Completed Jun 10, 2024
INTERVENTIONAL
  • t:slim X2 insulin pump with Tandem Freedom Algorithm
Diabetes Mellitus, Type 1
Lebrikizumab Pen Ease of Use in Participants With Atopic Dermatitis
Eli Lilly and Company
Phase 3
Completed Jun 10, 2024
INTERVENTIONAL
  • Lebrikizumab Pen
Atopic Dermatitis
FLT3 Clonal Evolution in Patients With Acute Myeloid Leukemia
Astellas Pharma Inc
Phase not applicable
Completed Jun 10, 2024
No interventions listed
Acute Myeloid Leukemia
Personalized Management of Autoimmune Diseases With AI-Guided (GenAIS TM) Dietary Supplementation
Triangel Scientific
Phase not applicable
Completed Jun 10, 2024
INTERVENTIONAL
  • AI-Guided Group
  • Control group
Autoimmune Diseases
A Study to Learn About the Benefit of Rimegepant Versus Triptans in Migraine Buddy App Users.
Phase not applicable
Completed Jun 10, 2024
No interventions listed
Migraine
Evaluating the Effect of a Supplement on Symptoms of Hormonal Imbalance.
Citruslabs
Phase not applicable
Completed Jun 10, 2024
INTERVENTIONAL
  • Perelel Health Hormonal Balance Support
Women's Health
Evaluating the Effect of a Supplement on Symptoms of Hormonal Imbalance.
Perelel Inc.
Phase not applicable
Completed Jun 10, 2024
INTERVENTIONAL
  • Perelel Health Hormonal Balance Support
Women's Health
Phase 1 Study in Diabetes Mellitus(Fed)
Huons Co., Ltd.
Phase 1
Completed Jun 10, 2024
INTERVENTIONAL
  • HUC2-344
  • HUC2-344-R1, HUC2-344-R2
Diabete Mellitus Diabetes
Lactoferrin Alone ,Iron Alone Vs Lactoferrin Plus Iron for Treatment of Iron Deficiency Anemia
Egymedicalpedia
Phase not applicable
Completed Jun 10, 2024
INTERVENTIONAL
  • Lactoferrin
Iron Deficiency Anemia
Technical Validation of MR Biomarkers of Obesity-Associated NAFLD
GE Healthcare
Phase not applicable
Completed Jun 11, 2024
OBSERVATIONAL
  • Liver biopsy
  • Magnetic Resonance Elastography (MRE)
Non-Alcoholic Fatty Liver Disease Non-alcoholic Steatohepatitis
Technical Validation of MR Biomarkers of Obesity-Associated NAFLD
Phase not applicable
Completed Jun 11, 2024
OBSERVATIONAL
  • Liver biopsy
  • Magnetic Resonance Elastography (MRE)
Non-Alcoholic Fatty Liver Disease Non-alcoholic Steatohepatitis
Technical Validation of MR Biomarkers of Obesity-Associated NAFLD
Siemens Medical Solutions
Phase not applicable
Completed Jun 11, 2024
OBSERVATIONAL
  • Liver biopsy
  • Magnetic Resonance Elastography (MRE)
Non-Alcoholic Fatty Liver Disease Non-alcoholic Steatohepatitis
Radiotherapy, Carboplatin/Paclitaxel and Nivolumab for High Risk HPV-related Head and Neck Cancer
Bristol-Myers Squibb
Phase 2
Completed Jun 11, 2024
INTERVENTIONAL
  • Carboplatin
  • Nivolumab
  • Paclitaxel
  • Radiation Therapy
Oropharynx Squamous Cell Carcinoma
Evaluation of Efficacy and Safety of Neoadjuvant Treatment With Pamrevlumab in Combination With Chemotherapy (Either Gemcitabine Plus Nab-paclitaxel or FOLFIRINOX) in Participants With Locally Advanced, Unresectable Pancreatic Cancer
FibroGen
Phase 3
Completed Jun 11, 2024
INTERVENTIONAL
  • Pamrevlumab + Gemcitabine + Nab-paclitaxel or Pamrevlumab + FOLFIRINOX
  • Placebo + Gemcitabine + Nab-paclitaxel or Placebo + FOLFIRINOX
Pancreatic Cancer Non-resectable
A Study Evaluating Oral Atogepant for the Prevention of Migraine in Japanese Participants With Chronic or Episodic Migraine
Phase 3
Completed Jun 11, 2024
INTERVENTIONAL
  • Atogepant 60 mg
Chronic Migraine Episodic Migraine
Oral ISL QM as PrEP in Cisgender Women at High Risk for HIV-1 Infection (MK-8591-022)
Merck Sharp & Dohme LLC
Phase 3
Completed Jun 11, 2024
INTERVENTIONAL
  • FTC/TDF
  • Islatravir
  • Placebo to FTC/TDF
  • Placebo to ISL
HIV-I Human Immunodeficiency Virus Type 1 Prophylaxis
Oral Nutritional Supplementation in Children at Risk of Undernutrition
Abbott Nutrition
Phase not applicable
Completed Jun 11, 2024
INTERVENTIONAL
  • Dietary counseling
  • Oral Nutritional Supplement
Undernutrition
BIO|CONCEPT.Amvia Study
Biotronik Australia Pty Ltd.
Phase not applicable
Completed Jun 11, 2024
INTERVENTIONAL
  • Amvia Sky pacemaker or CRT-P device
Bradycardia Heart Failure
BIO|CONCEPT.Amvia Study
Biotronik SE & Co. KG
Phase not applicable
Completed Jun 11, 2024
INTERVENTIONAL
  • Amvia Sky pacemaker or CRT-P device
Bradycardia Heart Failure
Impact on the Use of Antibiotics of a Multimodal Algorithm for the Diagnosis and Management of Acute Community-acquired Pneumonia in the Emergency Room
QIAGEN Gaithersburg, Inc
Phase not applicable
Completed Jun 11, 2024
INTERVENTIONAL
  • CRP dosage
  • chest scan without injection
  • multiplex PCR
Community-acquired Pneumonia
To Compare the Efficacy and Safety of INS068 and Insulin Glargine in Subjects With Type 2 Diabetes Mellitus Treated With Basal Insulin.
Jiangsu HengRui Medicine Co., Ltd.
Phase 3
Completed Jun 11, 2024
INTERVENTIONAL
  • INS068 injection
  • Insulin Glargine
Type 2 Diabetes Mellitus
Studying the Safety, Efficacy, and Pharmacokinetic Characteristics of BNCT in Patients With Recurrent High-grade Gliomas
Dawonmedax Co., Ltd.
Phase 1 / Phase 2
Completed Jun 11, 2024
INTERVENTIONAL
  • 500mg/kg/3hr followed by neutron irradiation to reach maximum brain dose of 11Gy-Eq
  • 500mg/kg/3hr followed by neutron irradiation to reach maximum brain dose of 13Gy-Eq
  • 500mg/kg/3hr followed by neutron irradiation to reach maximum brain dose of 9Gy-Eq
Recurrent Anaplastic Astrocytoma Recurrent Anaplastic Oligodendroglioma Recurrent Glioblastoma Recurrent High-grade Glioma
Assessment of Left Ventricular Filling Pressure by Applying Artificial Intelligence Algorithms to Left Atrial Speckle-tracking Echocardiography
Philips Healthcare
Phase not applicable
Past estimated: Jun 11, 2024
OBSERVATIONAL
  • Software algorithm
Echocardiography Heart Failure, Diastolic
Evaluation of the F&P Caramel Nasal Mask, US, 2023
Fisher and Paykel Healthcare
Phase not applicable
Past estimated: Jun 11, 2024
INTERVENTIONAL
  • F&P Caramel
Obstructive Sleep Apnea
Compare the Pharmacokinetics and Safety of BAT3306 Injection Versus KEYTRUDA® Administered in Healthy Male Subjects
Bio-Thera Solutions
Phase 1
Completed Jun 11, 2024
INTERVENTIONAL
  • Pembrolizumab injection
  • Recombinant Humanized Anti-PD-1 Monoclonal Antibody Solution for Injection
Healthy Male Subjects
Ovulation Triggering 2 Vs 3 Follicles
Clinique Ovo
Phase not applicable
Completed Jun 11, 2024
OBSERVATIONAL
  • Ovulation triggering
Infertility
A Study to Assess the Pharmacokinetics and Safety of Budesonide, Glycopyrronium, & Formoterol (BGF) Metered Dose Inhaler (MDI) Hydrofluoroolefin (HFO) With a Spacer (Treatment B), BGF MDI Hydrofluoroalkane (HFA) With a Spacer (Treatment A), as Well as BGF MDI HFO Without a Spacer (Treatment C).
AstraZeneca
Phase 1
Completed Jun 11, 2024
INTERVENTIONAL
  • AeroChamber Plus Flow-Vu spacer
  • Treatment A: BGF MDI HFA
  • Treatment B: BGF MDI HFO
  • Treatment C: BGF MDI HFO
Chronic Obstructive Pulmonary Disease
A Study to Assess the Pharmacokinetics and Safety of Budesonide, Glycopyrronium, & Formoterol (BGF) Metered Dose Inhaler (MDI) Hydrofluoroolefin (HFO) With a Spacer (Treatment B), BGF MDI Hydrofluoroalkane (HFA) With a Spacer (Treatment A), as Well as BGF MDI HFO Without a Spacer (Treatment C).
Parexel
Phase 1
Completed Jun 11, 2024
INTERVENTIONAL
  • AeroChamber Plus Flow-Vu spacer
  • Treatment A: BGF MDI HFA
  • Treatment B: BGF MDI HFO
  • Treatment C: BGF MDI HFO
Chronic Obstructive Pulmonary Disease
A Study to Learn About How Food and Esomeprazole Affect the Level of BAY2927088 in the Blood When Taken Together in Healthy Participants
Phase 1
Completed Jun 11, 2024
INTERVENTIONAL
  • BAY2927088
  • Esomeprazole
  • Food
Advanced Non-small Cell Lung Cancer EGFR Mutation HER2 Mutation Healthy Volunteers
A Clinical Trial to Assess the Efficacy and Safety of Subjects With Dry Eye Disease
Aldeyra Therapeutics, Inc.
Phase 3
Completed Jun 11, 2024
INTERVENTIONAL
  • Reproxalap Ophthalmic Solution (0.25%)
  • Vehicle Ophthalmic Solution
Dry Eye Disease
Comparison of Complarate® (Tocilizumab Biosimilar) and Actemra® in Patients With Rheumatoid Arthritis
AO GENERIUM
Phase 3
Completed Jun 11, 2024
INTERVENTIONAL
  • Actemra®
  • Complarate®
Rheumatoid Arthritis
A Study of Long-term Effects of Vedolizumab Subcutaneous in Adults With Ulcerative Colitis and Crohn's Disease
Phase 3
Completed Jun 12, 2024
INTERVENTIONAL
  • Vedolizumab SC
Colitis, Ulcerative Crohn's Disease
GOLDEN STUDY: A Study to Assess Safety and Efficacy of Multiple Doses of IONIS-FB-LRx in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (AMD)
Ionis Pharmaceuticals, Inc.
Phase 2
Completed Jun 12, 2024
INTERVENTIONAL
  • IONIS-FB-LRx
  • Placebo
Geographic Atrophy Macular Degeneration
Cryopreserved Human Umbilical Cord (TTAX01) for Late Stage, Complex Non-healing Diabetic Foot Ulcers (AMBULATE DFU)
BioTissue Holdings, Inc
Phase 3
Completed Jun 12, 2024
INTERVENTIONAL
  • Standard Care
  • TTAX01
Diabetic Foot Infection Non-healing Diabetic Foot Ulcer Non-healing Wound
LUMINOS-103: A Basket Trial of Safety & Efficacy of Lerapolturev With or Without Checkpoint Inhibitors
Istari Oncology, Inc.
Phase 1 / Phase 2
Completed Jun 12, 2024
INTERVENTIONAL
  • 5% DDM
  • Lerapolturev
Bladder Cancer Non-muscle-invasive Bladder Cancer Solid Tumor
Study of TG-1801 Alone or in Combination With Ublituximab in Subjects With B-Cell Lymphoma or Chronic Lymphocytic Leukemia
TG Therapeutics, Inc.
Phase 1
Completed Jun 12, 2024
INTERVENTIONAL
  • TG-1801
  • Ublituximab
Aggressive Lymphoma CLL DLBCL Follicular Lymphoma Indolent Lymphoma MCL Marginal Zone Lymphoma Mediastinal Large B-cell Lymphoma Richter's Transformation SLL
StrataPATH™ (Precision Indications for Approved Therapies)
Gilead Sciences
Phase 2
Completed Jun 12, 2024
INTERVENTIONAL
  • Fam-Trastuzumab Deruxtecan-Nxki
  • axitinib
  • encorafenib + binimetinib
  • enfortumab vedotin
  • lorlatinib
  • sacituzumab govitecan
  • talazoparib
Advanced Solid Tumor Cancer
StrataPATH™ (Precision Indications for Approved Therapies)
Merck Sharp & Dohme LLC
Phase 2
Completed Jun 12, 2024
INTERVENTIONAL
  • Fam-Trastuzumab Deruxtecan-Nxki
  • axitinib
  • encorafenib + binimetinib
  • enfortumab vedotin
  • lorlatinib
  • sacituzumab govitecan
  • talazoparib
Advanced Solid Tumor Cancer
StrataPATH™ (Precision Indications for Approved Therapies)
Phase 2
Completed Jun 12, 2024
INTERVENTIONAL
  • Fam-Trastuzumab Deruxtecan-Nxki
  • axitinib
  • encorafenib + binimetinib
  • enfortumab vedotin
  • lorlatinib
  • sacituzumab govitecan
  • talazoparib
Advanced Solid Tumor Cancer
StrataPATH™ (Precision Indications for Approved Therapies)
Strata Oncology
Phase 2
Completed Jun 12, 2024
INTERVENTIONAL
  • Fam-Trastuzumab Deruxtecan-Nxki
  • axitinib
  • encorafenib + binimetinib
  • enfortumab vedotin
  • lorlatinib
  • sacituzumab govitecan
  • talazoparib
Advanced Solid Tumor Cancer
A Study to Test Whether Two Different Doses of Avenciguat Help People With Liver Cirrhosis and High Blood Pressure in the Portal Vein (Main Vessel Going to the Live
Boehringer Ingelheim
Phase 2
Completed Jun 12, 2024
INTERVENTIONAL
  • Avenciguat (BI 685509)
  • Placebo matching Avenciguat (BI 685509)
Hypertension, Portal
A Study of Neoantigen mRNA Personalised Cancer in Patients With Advanced Solid Tumors
Stemirna Therapeutics
Recruiting Phase 1
Past estimated: Jun 12, 2024
INTERVENTIONAL
  • Neoantigen mRNA Personalised Cancer SW1115C3
Solid Tumor
Comparison of Efficacy, Pharmacodynamics, Safety, and Immunogenicity Between Bmab 1000 and Prolia® in Postmenopausal Women With Osteoporosis
Biocon Biologics UK Ltd
Phase 3
Completed Jun 12, 2024
INTERVENTIONAL
  • Bmab 1000
  • Prolia®
Postmenopausal Women With Osteoporosis
Evuzamitide in PET/CT to Measure Potential Therapeutic Response in ATTR
Attralus, Inc.
Phase 2
Completed Jun 12, 2024
INTERVENTIONAL
  • I 124-Evuzamitide
Transthyretin Amyloidosis
Clinical Evaluation of a Myopia Control Lens in Slowing Myopia Progression (CSL)
Essilor International
Phase not applicable
Completed Jun 12, 2024
INTERVENTIONAL
  • Test myopia control lenses (CSL)
Myopia
A Study to Evaluate Pharmacokinetics (PK) and Safety of Inaxaplin in Participants With Renal Impairment
Vertex Pharmaceuticals Incorporated
Phase 1
Completed Jun 12, 2024
INTERVENTIONAL
  • IXP
Renal Impairment
A Study to Test How Kidney Problems Influence the Blood Concentrations of Efgartigimod
Phase 1
Completed Jun 12, 2024
INTERVENTIONAL
  • Efgartigimod IV
Renal Impairment
Crome/Cobalt Respiration Study
Medtronic Cardiac Rhythm and Heart Failure
Phase not applicable
Completed Jun 12, 2024
OBSERVATIONAL
  • Enabling Sensor Research Holter Mode feature
Heart Failure
VH4524184 Proof-of-Concept in Treatment-Naïve Adults Living With HIV-1
GlaxoSmithKline
Phase 2
Completed Jun 12, 2024
INTERVENTIONAL
  • Placebo
  • VH4524184
HIV Infections
VH4524184 Proof-of-Concept in Treatment-Naïve Adults Living With HIV-1
ViiV Healthcare
Phase 2
Completed Jun 12, 2024
INTERVENTIONAL
  • Placebo
  • VH4524184
HIV Infections
Glin3: Assessment of the Glycemic Responses to Nutritional Products
Nutricia Research
Phase not applicable
Completed Jun 12, 2024
INTERVENTIONAL
  • 1st concept product series 2
  • 1st reference product series 2
  • 2nd concept product series 2
  • 2nd reference product series 2
  • 3rd concept product series 2
  • 3rd reference product series 2
  • 4th concept product series 2
  • 4th concept product seris 1
  • 5th concept product series 1
  • 5th concept product series 2
  • 6th concept product series 1
  • 6th concept product series 2
  • first concept product series 1
  • first reference product series 1
  • second concept product series 1
  • second reference product seies 1
  • third concept product series 1
  • third reference product series 1
Glycemic Response
A Phase 1 Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics, of VX-993
Vertex Pharmaceuticals Incorporated
Phase 1
Completed Jun 12, 2024
INTERVENTIONAL
  • Placebo
  • VX-993
Pain
Sitagliptin and Metformin Hydrochloride Tablets 50 mg/1000 mg Relative to Originator
Bio-innova Co., Ltd
Phase 1
Past estimated: Jun 12, 2024
INTERVENTIONAL
  • Sitagliptin and Metformin Hydrochloride Tablets Reference product
  • Sitagliptin and Metformin Hydrochloride Tablets Test product
Healthy Subjects
ETNA-MS Device Validation Study
Innodem Neurosciences
Phase not applicable
Past estimated: Jun 12, 2024
OBSERVATIONAL
  • Eye-Tracking
Multiple Sclerosis
Pharmacokinetics of HD-P023 and Co-administration of Teneligliptin and Empagliflozin High in Healthy Volunteers
Handok Inc.
Phase 1
Completed Jun 12, 2024
INTERVENTIONAL
  • Empagliflozin
  • HD-P023
  • Teneligliptin
Healthy Volunteers
A Study to Learn About How Itraconazole and Carbamazepine Affect the Level of BAY2927088 in the Blood When These Drugs Are Taken Together by Healthy Participants
Phase 1
Completed Jun 12, 2024
INTERVENTIONAL
  • BAY2927088
  • Carbamazepine
  • Itraconazole
Advanced Non-small Cell Lung Cancer EGFR Mutation HER2 Mutation Healthy Volunteers
Observational Cohort Study Evaluating the Effectiveness of an Educational Program (NGAYDAUTIEN) in Combination With Perindopril and Amlodipine Single-Pill Combination in Hypertensive Patients naïve of Antihypertensive Treatments.
Servier Affaires Médicales
Phase not applicable
Completed Jun 12, 2024
No interventions listed
Hypertension
Secur-Fit Advanced Outcomes Study
Stryker Orthopaedics
Phase not applicable
Completed Jun 13, 2024
INTERVENTIONAL
  • Secur-Fit Advanced Hip Stem
Arthroplasty, Replacement, Hip
A Research Study of How Well Macimorelin Works to Find Out if Children Have a Lack of Growth Hormone and How Safe it is
AEterna Zentaris
Phase 3
Completed Jun 13, 2024
INTERVENTIONAL
  • Arginine
  • Clonidine
  • Macimorelin
Growth Hormone Deficiency
A Study on the Immune Response and Safety of Various Potencies of an Investigational Chickenpox Vaccine Compared With a Marketed Chickenpox Vaccine, Given to Healthy Children 12 to 15 Months of Age
GlaxoSmithKline
Phase 2
Completed Jun 13, 2024
INTERVENTIONAL
  • 13-valent pneumococcal conjugate vaccine
  • Hepatitis A vaccine
  • Investigational varicella vaccine high potency
  • Investigational varicella vaccine low potency
  • Investigational varicella vaccine medium potency
  • Licensed varicella vaccine Lot 1
  • Licensed varicella vaccine Lot 2
  • Measles, mumps, and rubella vaccine
Chickenpox
Trilaciclib in Patients Receiving Sacituzumab Govitecan-hziy for Triple Negative Breast Cancer
G1 Therapeutics, Inc.
Phase 2
Completed Jun 13, 2024
INTERVENTIONAL
  • Sacituzumab Govitecan-hziy
  • Trilaciclib
Triple Negative Breast Cancer
Study of Interest of Stiripentol and Carbamazepine in the Treatment of Patients With Pharmacoresistant Focal Epilepsies
Biocodex
Phase 4
Completed Jun 13, 2024
INTERVENTIONAL
  • Stiripentol
Pharmacoresistant Focal Epilepsies
A Randomized, Double-Blind, Placebo-Controlled Study With an Open-Label Period on Efficacy and Safety of Fremanezumab in Chinese Adults With Migraine
Teva Branded Pharmaceutical Products R&D, Inc.
Phase 3
Completed Jun 13, 2024
INTERVENTIONAL
  • Fremanezumab
  • Placebo
Migraine
A Research Study Looking at the Safety of Multiple Doses of ZP8396 and How it Works in the Body of Healthy Participants
Zealand Pharma
Phase 1
Completed Jun 13, 2024
INTERVENTIONAL
  • Drug: Placebo (ZP8396)
  • ZP8396
Healthy Volunteers Obese Overweight
Phenotyping Responses to Systemic Corticosteroids in the Management of Asthma Attacks
BioMérieux
Phase not applicable
Completed Jun 13, 2024
OBSERVATIONAL
  • Visit 1: Clinical exam and questionnaires
  • Visit 1: Inflammometry
  • Visit 1: Respiratory physiology
  • Visit 2: Clinical exam and questionnaires
  • Visit 2: Inflammometry
  • Visit 2: Respiratory physiology
  • Visit 3: e-mail
Asthma
Visual Performance of the Vivity IOL in Post-myopic LASIK and PRK Patients
Phase not applicable
Completed Jun 13, 2024
OBSERVATIONAL
  • Vivity IOL
Cataract
Investigating Mild Cognitive Impairment in Patients And Controls With TD-fNIRS
Phase not applicable
Completed Jun 13, 2024
OBSERVATIONAL
  • fNIRS measurement
Mild Cognitive Impairment
Phase I Clinical Study of ZL-82 Tablets
Chengdu Zenitar Biomedical Technology Co., Ltd
Phase 1
Completed Jun 13, 2024
INTERVENTIONAL
  • ZL-82 100mg
  • ZL-82 12.5mg
  • ZL-82 200mg
  • ZL-82 25mg
  • ZL-82 300mg
  • ZL-82 450mg
  • ZL-82 50mg
  • ZL-82 600mg
  • ZL-82 placebo 100mg
  • ZL-82 placebo 200mg
  • ZL-82 placebo 25mg
  • ZL-82 placebo 300mg
  • ZL-82 placebo 450mg
  • ZL-82 placebo 50mg
  • ZL-82 placebo 600mg
  • zL-82 placebo 12.5mg
Inflammatory Bowel Disease - IBD1 Rheumatoid Arthritis (RA)
A Study to Assess the Relative Bioavailability of 5 mg Mavacamten Opened Capsule Administered Via Nasogastric Tube Compared to Intact Oral 5 mg Mavacamten in Healthy Participants
Bristol-Myers Squibb
Phase 1
Completed Jun 13, 2024
INTERVENTIONAL
  • Treatment A: Mavacamten intact oral capsule
  • Treatment B: Mavacamten open capsule in suspension
  • Treatment C: Mavacamten open capsule in suspension administered via nasogastric tube (NGT)
Healthy Volunteers
A Clinical Trial to Evaluate the Food Effect of CKD-378
Chong Kun Dang Pharmaceutical
Phase 1
Completed Jun 13, 2024
INTERVENTIONAL
  • CKD-378, QD, PO
Type II Diabetes Mellitus
Accuracy of the EvieMED Ring Pulse Oximeter in Profound Hypoxia
Movano Health
Phase not applicable
Past estimated: Jun 13, 2024
OBSERVATIONAL
  • Pulse oximeter
Hypoxia
Feasibility of the LUM Imaging System for Detection of Cancer to the Brain
Lumicell, Inc.
Phase not applicable
Completed Jun 14, 2024
INTERVENTIONAL
  • LUM Imaging System
Glioblastoma Low Grade Glioma of Brain Metastasis to Brain
PROactive Evaluation of Function to Avoid CardioToxicity
Myocardial Solutions
Phase 2
Completed Jun 14, 2024
INTERVENTIONAL
  • MyoStrain®
Breast Cancer Cardiotoxicity Leukemia Lung Cancer Lymphoma Myeloma Sarcoma
OLE of Phase 2b/3 Study ANAVEX2-73-AD-004
Anavex Australia Pty Ltd.
Phase 2 / Phase 3
Completed Jun 14, 2024
INTERVENTIONAL
  • ANAVEX2-73
Alzheimer Disease
OLE of Phase 2b/3 Study ANAVEX2-73-AD-004
Anavex Germany GmbH
Phase 2 / Phase 3
Completed Jun 14, 2024
INTERVENTIONAL
  • ANAVEX2-73
Alzheimer Disease
OLE of Phase 2b/3 Study ANAVEX2-73-AD-004
Anavex Life Sciences Corp.
Phase 2 / Phase 3
Completed Jun 14, 2024
INTERVENTIONAL
  • ANAVEX2-73
Alzheimer Disease
Study to Evaluate the Efficacy (Effect on Disease) and Safety of Finerenone on Morbidity (Events Indicating Disease Worsening) & Mortality (Death Rate) in Participants With Heart Failure and Left Ventricular Ejection Fraction (Proportion of Blood Expelled Per Heart Stroke) Greater or Equal to 40%
Phase 3
Completed Jun 14, 2024
INTERVENTIONAL
  • Finerenone (BAY94-8862)
  • Placebo
Heart Failure
A Study to Evaluate the Safety, Reactogenicity, and Effectiveness of mRNA-1273 Vaccine in Adolescents 12 to <18 Years Old to Prevent COVID-19
ModernaTX, Inc.
Phase 2 / Phase 3
Completed Jun 14, 2024
INTERVENTIONAL
  • Placebo
  • mRNA-1273
  • mRNA-1273.222
SARS-CoV-2
A Trial Monitoring Therapy Pathways of Asthma Patients Treated With an Extrafine ICS/LABA/LAMA Single-inhaler Triple Therapy in a Real-world Setting and Characterizing the Effects on Health-related Out-comes
Chiesi UK
Phase not applicable
Completed Jun 14, 2024
OBSERVATIONAL
  • Non-interventional
Asthma
A Trial Monitoring Therapy Pathways of Asthma Patients Treated With an Extrafine ICS/LABA/LAMA Single-inhaler Triple Therapy in a Real-world Setting and Characterizing the Effects on Health-related Out-comes
Gesellschaft für Therapieforschung mbH
Phase not applicable
Completed Jun 14, 2024
OBSERVATIONAL
  • Non-interventional
Asthma
A Study to Evaluate the Safety and Effectiveness of a Digital Therapeutic
Oui Therapeutics, Inc.
Phase 2 / Phase 3
Completed Jun 14, 2024
INTERVENTIONAL
  • OTX-000
  • OTX-202
Suicidal Ideation Suicide, Attempted
A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD0780 in Healthy Subjects
AstraZeneca
Phase 1
Completed Jun 14, 2024
INTERVENTIONAL
  • AZD0780
  • Placebo
  • Rosuvastatin
Dyslipidemia
A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD0780 in Healthy Subjects
Parexel
Phase 1
Completed Jun 14, 2024
INTERVENTIONAL
  • AZD0780
  • Placebo
  • Rosuvastatin
Dyslipidemia
A Study to Evaluate D-1553 in Combination Therapy in Non-Small Cell Lung Cancer
InventisBio Co., Ltd
Phase 1 / Phase 2
Completed Jun 14, 2024
INTERVENTIONAL
  • D-1553
  • Other
NSCLC
Evaluation of Quality of Vision and Visual Outcomes With Bilateral Implantation of the Clareon PanOptix Intraocular Lens
Phase not applicable
Completed Jun 14, 2024
OBSERVATIONAL
  • The Clareon™ PanOptix™ Trifocal (toric and non-toric models)
Cataract
Effectiveness and Safety of Restylane Lyft Lidocaine for Jawline Definition
Galderma R&D
Phase not applicable
Completed Jun 14, 2024
INTERVENTIONAL
  • Restylane Lyft Lidocaine
Jawline Definition
Immuno-positron Emission Tomography Study of 89Zr-S095012 in Patients With Advanced Solid Tumours
ADIR, a Servier Group company
Phase 1
Completed Jun 14, 2024
INTERVENTIONAL
  • 89Zr-S095012 tracer and S095012 will be administered via an IV infusion
Advanced Solid Tumor
A Study in Male and Female Adult Participants With Chronic Rhinosinusitis With Nasal Polyps In the Greater Gulf Region
Phase not applicable
Completed Jun 14, 2024
No interventions listed
Chronic Rhinosinusitis With Nasal Polyps
A Study in Healthy Men to Test How Well Multiple Doses of BI 1839100 Are Tolerated and How BI 1839100 Influences the Amount of Other Medicines in the Blood
Boehringer Ingelheim
Phase 1
Completed Jun 14, 2024
INTERVENTIONAL
  • BI 1839100
  • Placebo matching BI 1839100
  • digoxin
  • midazolam
  • rosuvastatin
Healthy
Single and Multiple Ascending Dose Study to Assess Safety, Tolerability and Pharmacokinetics of NM-101
Neuramedy Co. Ltd.
Not yet recruiting Phase 1
Past estimated: Jun 14, 2024
INTERVENTIONAL
  • NM-101
  • Placebo
Parkinson Disease
Single and Multiple Ascending Dose Study to Assess Safety, Tolerability and Pharmacokinetics of NM-101
Quotient Sciences
Not yet recruiting Phase 1
Past estimated: Jun 14, 2024
INTERVENTIONAL
  • NM-101
  • Placebo
Parkinson Disease
The Efficacy and Safety of Protoxin in Subjects With Moderate to Severe Glabellar Lines
Protox Inc.
Phase 3
Completed Jun 14, 2024
INTERVENTIONAL
  • PROTOXIN
Glabellar Frown Lines
Pharmacokinetics and Pharmacodynamics of Subcutaneous vs Intravenous Furosemide in Healthy Volunteers
scPharmaceuticals, Inc.
Phase 1
Completed Jun 14, 2024
INTERVENTIONAL
  • Furosemide USP
  • SCP-111
Fluid Overload Heart Failure
UV1 Vaccine With Pembrolizumab for Patients With Unresectable or Metastatic Melanoma
Ultimovacs ASA
Phase 1
Completed Jun 15, 2024
INTERVENTIONAL
  • GM-CSF
  • UV1
Malignant Melanoma
EmboTrap ® II Revascularization Device (Neuravi) in Acute Ischemic Stroke
Neuravi Limited
Recruiting Phase not applicable
Past estimated: Jun 15, 2024
OBSERVATIONAL
  • Mechanical thrombectomy with EmboTrap ® II Device
Acute Ischemic Stroke
Radiotherapy in IDH Mutated Glioma: Evaluation of Late Outcomes
HollandPTC
Phase not applicable
Completed Jun 15, 2024
No interventions listed
Astrocytoma, Grade II Astrocytoma, Grade III Oligodendroglioma Oligodendroglioma, Anaplastic
Ticagrelor With and Without Aspirin in Patients With Diabetes Mellitus
AstraZeneca
Phase 4
Completed Jun 15, 2024
INTERVENTIONAL
  • Clopidogrel with aspirin
  • Ticagrelor monotherapy
  • Ticagrelor plus aspirin
Coronary Artery Disease Diabetes Mellitus, Type 2
Motivating Occupational Virtual Experiences In Therapy for Kids
Barron Associates, Inc.
Phase not applicable
Completed Jun 15, 2024
INTERVENTIONAL
  • MOVE-IT Intervention
  • UCT Control
Occupational Therapy Virtual Reality
In Vitro Analysis of Human Urine With the CloudCath Device
CloudCath
Phase not applicable
Past estimated: Jun 15, 2024
OBSERVATIONAL
  • Spectral characteristics assessment
Urinary Tract Infections
Management of Moderate POstoperative Recurrence in Crohn's Disease: a randoMizEd contROLled Trial of Therapeutic Escalation, the POMEROL Trial. (POMEROL)
Celltrion
Recruiting Phase 4
Past estimated: Jun 15, 2024
INTERVENTIONAL
  • Immunosuppressors (Thiopurines or Methotrexate)
  • Infliximab CT-P13
Crohn Disease
Research and Development of Novel Quantitative Magnetic Resonance Imaging (MRI) Techniques in a Single Scan for Multiple Organ Application
Perspectum
Phase not applicable
Past estimated: Jun 15, 2024
No interventions listed
Multiple
Sacral Fracture Fusion/Fixation for Rapid Rehabilitation
SI-BONE, Inc.
Phase not applicable
Completed Jun 15, 2024
INTERVENTIONAL
  • Non-Surgical Management
  • Surgical Intervention
Fracture;Pelvis Fragility Fracture Insufficiency Fractures Osteoporosis Sacral Fracture Sacroiliac; Fusion
Study of AT-527 in Subjects With Normal and Impaired Renal Function
Atea Pharmaceuticals, Inc.
Phase 1
Completed Jun 15, 2024
INTERVENTIONAL
  • AT-527
  • AT-527 and Probenecid
Healthy Volunteer Renal Impairment
Evaluation of CG-100 Intraluminal Bypass Device
Colospan Ltd.
Phase not applicable
Past estimated: Jun 15, 2024
INTERVENTIONAL
  • CG-100 Intraluminal Bypass Device
Colorectal Cancer
A Phase I Study of BC3402 as a Single Agent in Patients With MDS and CMML
Biocity Biopharmaceutics Co., Ltd.
Phase 1
Past estimated: Jun 15, 2024
INTERVENTIONAL
  • BC3402 Injection
Hematologic Malignancy
Selective Lipopolysaccharide Hemosorption in Maternal Sepsis
Efferon JSC
Phase not applicable
Completed Jun 15, 2024
INTERVENTIONAL
  • Efferon LPS
Maternal sepsIs
An Observational Study to Learn More How Chronic Kidney Disease Gradually Changes Over Time in Adults Using Electronic Healthcare Records (CKD Natural History Study)
Phase not applicable
Completed Jun 15, 2024
OBSERVATIONAL
  • No Intervention
Chronic Kidney Disease
Safety and Tolerance of Increased Doses of SHR-2106 Injection in Healthy Subjects
Guangdong Hengrui Pharmaceutical Co., Ltd
Phase 1
Past estimated: Jun 15, 2024
INTERVENTIONAL
  • SHR-2106 injection or placebo
Kidney Transplantation
Effect of an Exploratory Vehicle on Meibomian Gland Dysfunction in Patients With Demodex
Tarsus Pharmaceuticals, Inc.
Phase 2
Past estimated: Jun 15, 2024
INTERVENTIONAL
  • Vehicle of TP-03
Blepharitis Demodectic Blepharitis Demodex Infestation of Eyelid Meibomian Gland Dysfunction
A Randomized-Controlled Trial to Examine the Effects of a Daily Probiotic Supplement on Common Symptoms of Menopause
Citruslabs
Phase not applicable
Completed Jun 15, 2024
INTERVENTIONAL
  • Placebo
  • Provitalize Natural Menopause Probiotic
Menopause
A Randomized-Controlled Trial to Examine the Effects of a Daily Probiotic Supplement on Common Symptoms of Menopause
Maneuver Marketing
Phase not applicable
Completed Jun 15, 2024
INTERVENTIONAL
  • Placebo
  • Provitalize Natural Menopause Probiotic
Menopause
A Multi-center, Early Feasibility Study of Using the Mechanical Tissue Resuscitation™ (MTR™) Therapy System for Removal of Excess Fluid in Subjects Who Have Had a Portion of Their Skull Removed to Expose the Dura/Brain and Require Drainage for Fluid Removal.
Renovo Concepts, Inc.
Phase not applicable
Past estimated: Jun 15, 2024
INTERVENTIONAL
  • Mechanical Tissue Resuscitation (MTR™)
Clinical Need for Craniotomy or Craniectomy
The Effect of the Probiotic Strains on Bone Mineral Density in Postmenopausal Women
Nordic Biotic Sp. z o.o.
Phase not applicable
Past estimated: Jun 15, 2024
INTERVENTIONAL
  • Placebo
  • Probiotic
Bone Density, Low Osteoporosis, Postmenopausal
A Multi-site Clinical Evaluation of Capillary Blood Samples Collected Using the Tasso+SST Device for Downstream Analyte Testing
Tasso Inc.
Phase not applicable
Past estimated: Jun 15, 2024
OBSERVATIONAL
  • Tasso+SST
Serum Analytes
Bioavailability and Food Effects of HRS-7535 Tablets With Different Formulating Processes in Healthy Subjects
Shandong Suncadia Medicine Co., Ltd.
Phase 1
Past estimated: Jun 15, 2024
INTERVENTIONAL
  • HRS-7535(C)Tablets
  • HRS-7535(D)Tablets
Type 2 Diabetes Mellitus
Comparative Study of Two Hyaluronic Acid Formulation in the Management of Knee Osteoarthritis
Fidia Farmaceutici s.p.a.
Phase not applicable
Completed Jun 15, 2024
INTERVENTIONAL
  • Hymovis ONE
  • Monovisc
Osteoarthritis, Knee
Breathe-Easy: Hayfever Care for Patients With Seasonal Allergic Rhinitis
Innowage Limited
Phase not applicable
Completed Jun 15, 2024
INTERVENTIONAL
  • Hayfever Care
  • Wait-list Control
Allergic Rhinitis Allergy Pollen Hayfever
Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Recifercept in Healthy Chinese Participants
Phase 1
Past estimated: Jun 16, 2024
INTERVENTIONAL
  • Recifercept
Healthy
Impact of BacT/Alert® VIRTUO®, BioFire® Blood Culture Identification 2-BCID2 and REVEAL® (bioMérieux) on the Optimization of Antibiotic Therapy for Gram-negative Bacteremia in the ICU
BioMérieux
Phase not applicable
Completed Jun 16, 2024
OBSERVATIONAL
  • Innovative diagnostic technologies
  • Reference diagnostic technique
Bacteremia
A Trial to Investigate the Single Dose Pharmacokinetics of Insulin Degludec/Liraglutide in Healthy Chinese Subjects
Tonghua Dongbao Pharmaceutical Co.,Ltd
Phase 1
Past estimated: Jun 16, 2024
INTERVENTIONAL
  • Xultophy®
  • insulin degludec/liraglutide
Healthy
A Study of LGK974 in Patients With Malignancies Dependent on Wnt Ligands
Novartis Pharmaceuticals
Phase 1
Completed Jun 17, 2024
INTERVENTIONAL
  • LGK974
  • PDR001
BRAF Mutant Colorectal Cancer Cervical Squamous Cell Cancer Esophageal Squamous Cell Cancer Head and Neck Squamous Cell Cancer Lung Squamous Cell Cancer Melanoma Pancreatic Cancer Triple Negative Breast Cancer
Multi-Arm Study to Test the Efficacy of Immunotherapeutic Agents in Multiple Sarcoma Subtypes
MedImmune LLC
Phase 2
Completed Jun 17, 2024
INTERVENTIONAL
  • Durvalumab
  • Tremelimumab
Advanced and/or Metastatic Sarcoma
The Late Presenter Treatment Optimisation Study
Gilead Sciences
Phase 3
Completed Jun 17, 2024
INTERVENTIONAL
  • Biktarvy
  • Symtuza
HIV/AIDS
The Late Presenter Treatment Optimisation Study
Janssen Pharmaceuticals
Phase 3
Completed Jun 17, 2024
INTERVENTIONAL
  • Biktarvy
  • Symtuza
HIV/AIDS
Randomized Placebo Controlled Trial Evaluating the Efficacy of Pimavanserin, a Selective Serotonin 5-HydroxyTryptamine-2A (5HT2A) Inverse Agonist, to Treat Impulse Control Disorders in Parkinson's Disease.
ACADIA Pharmaceuticals Inc.
Phase 2
Completed Jun 17, 2024
INTERVENTIONAL
  • Active drug: pimavanserin 17mg (2 strength tablets)
  • Assessment of cognition
  • Assessment of depression
  • Assessment of motor and non-motors symptoms of PD Evaluation of hyper- and hypodopaminergic behaviors
  • Assessment of quality of life
  • Assessment of severity of ICD (impulse control disorders)
  • Assessment of severity of Parkinson Disease
  • Blood analysis
  • Cardiac monitoring
  • Placebo: 2 tablets containing same excipients except active compound
Parkinson Disease
Study to Evaluate Safety and Clinical Activity of AB122 in Biomarker Selected Participants With Advanced Solid Tumors
Arcus Biosciences, Inc.
Phase 1
Completed Jun 17, 2024
INTERVENTIONAL
  • zimberelimab
Advanced Solid Tumors
Study to Evaluate Safety and Clinical Activity of AB122 in Biomarker Selected Participants With Advanced Solid Tumors
Gilead Sciences
Phase 1
Completed Jun 17, 2024
INTERVENTIONAL
  • zimberelimab
Advanced Solid Tumors
Study to Evaluate Safety and Clinical Activity of AB122 in Biomarker Selected Participants With Advanced Solid Tumors
Strata Oncology
Phase 1
Completed Jun 17, 2024
INTERVENTIONAL
  • zimberelimab
Advanced Solid Tumors
Long Term Arrhythmia Risk and Cardiovascular Events in Hematopoietic Stem Cell Transplant
Medtronic
Phase not applicable
Completed Jun 17, 2024
OBSERVATIONAL
  • HSCT Patients
Atrial Fibrillation Atrial Flutter Hematopoietic Stem Cell Transplant
The Pharmacokinetic and Pharmacodynamic Effects of Oral Cannabidiol (CBD) Under Acute and Chronic Exposure Conditions
Canopy Growth Corporation
Phase 1
Completed Jun 17, 2024
INTERVENTIONAL
  • CBD
  • THC
Cannabis, Drug Effects
Device to Assist With Abdominal Access During Laparoscopic Surgery
TauTona Group
Phase not applicable
Completed Jun 17, 2024
INTERVENTIONAL
  • Standard of Care (SOC)
  • TauTona Pneumoperitoneum Assist Device (TPAD)
Laparoscopic Surgery
PiXL as a Treatment for Low Grade Myopia
Glaukos Corporation
Phase not applicable
Past estimated: Jun 17, 2024
INTERVENTIONAL
  • PiXL
Myopia Refractive Errors
Safety and Efficacy of Hyperbaric Oxygen Therapy for Long COVID Syndrome
Karolinska Trial Alliance
Phase 2
Completed Jun 17, 2024
INTERVENTIONAL
  • Hyperbaric oxygen
  • Sham treatment
COVID-19 Post COVID Condition Post COVID-19 Condition Post COVID-19 Condition, Unspecified Post-Acute COVID-19 Syndrome Post-COVID Syndrome
Evaluating the Safety, Tolerability, and Pharmacokinetics of BAT1006
Bio-Thera Solutions
Phase 1
Completed Jun 17, 2024
INTERVENTIONAL
  • BAT1006
Advanced Solid Tumor
A Study of ABM-1310 in Patients With BRAF V600-Mutant Advanced Solid Tumors
ABM Therapeutics Shanghai Company Limited
Phase 1
Completed Jun 17, 2024
INTERVENTIONAL
  • ABM-1310
Advanced Solid Tumor BRAF V600 Mutation
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Monoclonal Antibody (mAb) in Patients With IPF
Chiesi Farmaceutici S.p.A.
Phase 1
Completed Jun 17, 2024
INTERVENTIONAL
  • CHF10067 high dose
  • CHF10067 intermediate dose
  • CHF10067 starting dose
  • Placebo
Idiopathic Pulmonary Fibrosis
A Study For Treatment Of Paroxysmal Atrial Fibrillation (PAF) With The THERMOCOOL SMARTTOUCH SF Catheter and TRUPULSE Generator
Biosense Webster, Inc.
Phase not applicable
Completed Jun 17, 2024
INTERVENTIONAL
  • Pulsed Field (PF) /Radiofrequency (RF) Catheter ablation
Atrial Fibrillation
An Observational Study of Moderna COVID-19 Bivalent Vaccines (Original and Omicron BA.4/BA.5) and 2023 Updated mRNA COVID-19 Vaccines (XBB.1.5)
ModernaTX, Inc.
Phase not applicable
Completed Jun 17, 2024
OBSERVATIONAL
  • Moderna 2023 Updated COVID-19 vaccine (XBB.1.5)
  • Moderna COVID-19 Vaccine
  • Moderna mRNA1273.222 Booster
  • Pfizer 2023 Updated COVID-19 vaccine (XBB.1.5)
  • Pfizer COVID-19 Vaccine
COVID-19
Consistently Assess Signs and Symptom of Heart Failure
Recruiting Phase not applicable
Past estimated: Jun 17, 2024
INTERVENTIONAL
  • New York Heart Association Classification Guide
Heart Failure Heart Failure With Preserved Ejection Fraction Heart Failure With Reduced Ejection Fraction
Mindfulness-based Cognitive Coping for ADRD Caregivers
Photozig, Inc.
Phase 2
Completed Jun 17, 2024
INTERVENTIONAL
  • Mindfulness-based Cognitive Coping
  • Traditional Educational/Resources Program
Caregiver Stress
The Prevalence Evaluation of Systemic Lupus Erythematosus in Russian Patients With Reproductive Issues (PRISMA)
AstraZeneca
Phase not applicable
Completed Jun 17, 2024
No interventions listed
Systemic Lupus Erythematosus
Safety and Immunogenicity of a Booster Vaccination with an Adapted Vaccine
Hipra Scientific, S.L.U
Phase 2 / Phase 3
Completed Jun 17, 2024
INTERVENTIONAL
  • Comirnaty Omicron XBB1.5
  • PHH-1V81
SARS-CoV2 Infection
A Study to Evaluate Early Treatment Outcomes With Miebo™ in Subjects With Dry Eye Disease
Bausch & Lomb Incorporated
Phase 4
Completed Jun 17, 2024
INTERVENTIONAL
  • Miebo
Dry Eye
A Study to Investigate the Pharmacokinetics of Baxdrostat When Given Alone and in Combination With Itraconazole in Healthy Participants
AstraZeneca
Phase 1
Completed Jun 17, 2024
INTERVENTIONAL
  • Baxdrostat
  • Itraconazole
Healthy Participants
Evaluate the Efficacy and Safety of TTYP01 Tablets in the Treatment of Acute Ischemic Stroke
Shanghai Auzone Biological Technology Co., Ltd.
Phase 3
Completed Jun 17, 2024
INTERVENTIONAL
  • Placebo (Simulant TTYP01 Tablets)
  • TTYP01 tablets
Acute Ischemic Stroke
This is a Phase 1 Study in Which Healthy Volunteers and Participants with Chronic HBV Infection Will Receive HT-101 or Placebo and Will Be Assessed for Safety, Tolerability, Pharmacokinetics (PK), and Antiviral Activity
Suzhou HepaThera Biotech Co., Ltd.
Phase 1
Completed Jun 17, 2024
INTERVENTIONAL
  • HT-101
  • Placebo
Chronic Hepatitis B
Efficacy of Oral Azacitidine Plus Best Supportive Care as Maintenance Therapy in Subjects With Acute Myeloid Leukemia (AML) in Complete Remission
Celgene
Phase 3
Completed Jun 18, 2024
INTERVENTIONAL
  • Oral Azacitidine
  • Placebo
Leukemia, Myeloid, Acute
Feasibility Study of the Tendyne Mitral Valve System in Mitral Annular Calcification
Abbott Medical Devices
Phase not applicable
Completed Jun 18, 2024
INTERVENTIONAL
  • Tendyne Mitral Valve System
Cardiovascular Diseases Heart Valve Calcification Heart Valve Diseases Mitral Annular Calcification Mitral Annulus Calcification Mitral Insufficiency Mitral Regurgitation Mitral Valve Disease Valve Heart Disease
Study of a High-Dose Aflibercept in Participants With Diabetic Eye Disease
Phase 2 / Phase 3
Completed Jun 18, 2024
INTERVENTIONAL
  • High-dose aflibercept
  • aflibercept
Diabetic Macular Edema Type 1 Diabetes Mellitus Type 2 Diabetes Mellitus
Study of a High-Dose Aflibercept in Participants With Diabetic Eye Disease
Regeneron Pharmaceuticals
Phase 2 / Phase 3
Completed Jun 18, 2024
INTERVENTIONAL
  • High-dose aflibercept
  • aflibercept
Diabetic Macular Edema Type 1 Diabetes Mellitus Type 2 Diabetes Mellitus
A Study of Fruquintinib in Combination with Tislelizumab in Advanced Solid Tumors
BeiGene
Phase 1 / Phase 2
Completed Jun 18, 2024
INTERVENTIONAL
  • Fruquintinib
  • Tislelizumab
Colorectal Cancer Endometrial Cancer Solid Tumor, Unspecified, Adult Triple Negative Breast Cancer
A Study of Fruquintinib in Combination with Tislelizumab in Advanced Solid Tumors
Hutchison Medipharma Limited
Phase 1 / Phase 2
Completed Jun 18, 2024
INTERVENTIONAL
  • Fruquintinib
  • Tislelizumab
Colorectal Cancer Endometrial Cancer Solid Tumor, Unspecified, Adult Triple Negative Breast Cancer
Medacta NextAR TKA Pivotal Trial
Medacta International SA
Phase not applicable
Completed Jun 18, 2024
INTERVENTIONAL
  • NextAR TKA system
Musculoskeletal Diseases
A Study on How Vedolizumab is Given and the Outcomes for Adults With Inflammatory Bowel Disease (VARIETY-Belgium)
Phase not applicable
Completed Jun 18, 2024
No interventions listed
Colitis, Ulcerative Crohns Disease Inflammatory Bowel Diseases
Study to Evaluate the Safety and Tolerability of CC-92328 in Participants With Relapsed and/or Refractory Multiple Myeloma
Celgene
Phase 1
Completed Jun 18, 2024
INTERVENTIONAL
  • CC-92328
Multiple Myeloma
Clinical Evaluation of Fractional Bi-Polar Radio-Frequency for Symptoms of Vulvovaginal Atrophy
InMode MD Ltd.
Phase not applicable
Completed Jun 18, 2024
INTERVENTIONAL
  • MorpheusV Applicator
Vaginal Atrophy
A Study in Male and Female Adult Patients With Atopic Dermatitis Treated With Dupilumab in Taiwan
Phase not applicable
Completed Jun 18, 2024
No interventions listed
Atopic Dermatitis
Pivotal Trial for a Synthetic Tissue Substitute for Concealment of Artificial Ocular Implants
CorNeat Vision Ltd.
Phase not applicable
Completed Jun 18, 2024
INTERVENTIONAL
  • CorNeat EverPatch
Glaucoma Eye Tissue Breakdown
Clinical Efficacy and Safety Evaluation of Teneligliptin in Type 2 Diabetes Who Have Inadequate GlycemIc Control With Empaglyflozin 25 mg and Metformin
Handok Inc.
Phase 3
Completed Jun 18, 2024
INTERVENTIONAL
  • Teneligliptin (as Teneligliptin Hydrobromide) 20 Mg Oral Tablet
  • Teneligliptin Placebo Oral Tablet
Type 2 Diabetes
Post-transplant Flotetuzumab for AML
MacroGenics
Phase 1
Completed Jun 18, 2024
INTERVENTIONAL
  • Flotetuzumab
Leukemia, Myeloid, Acute
Oral Rehydration Solutions in Healthy Adult Athletes
Abbott Nutrition
Phase not applicable
Completed Jun 18, 2024
INTERVENTIONAL
  • Control Group
  • Oral Rehydration Solution
  • Water
Hydration
A Randomized Controlled Trial to Compare the Glycemic Control, With or Without the Connected Solution, of Adult Type 2 Diabetic Participants on Basal Insulin in Taiwan
Phase not applicable
Completed Jun 18, 2024
INTERVENTIONAL
  • Connected Solution with H2S app which connects with blood glucose meter (BGM)
Type 2 Diabetes Mellitus
First in Human Study Evaluating Single Ascending Oral Doses of YCT-529 in Healthy Males
YourChoice Therapeutics, Inc.
Phase 1
Completed Jun 18, 2024
INTERVENTIONAL
  • YCT-529
  • YCT-529 Placebo
Male Contraception
A Study to Evaluate the Safety and Immunogenicity of a Single Dose of Adsorbed Tetanus Vaccine in a Population Aged 18 Years and Over
CanSino Biologics Inc.
Phase 1
Completed Jun 18, 2024
INTERVENTIONAL
  • TT
  • TTVA
Tetanus
A Study to Evaluate the Effect of Jaktinib on QT/QTc Interval in Healthy Participants
Suzhou Zelgen Biopharmaceuticals Co.,Ltd
Phase 1
Completed Jun 18, 2024
INTERVENTIONAL
  • Jaktinib
  • Placebo
Healthy Participants
A Study to Assess the Potential for Gastric-pH Dependent Drug-Drug Interactions of BIIB122 With a Proton Pump Inhibitor in Healthy Participants
Phase 1
Completed Jun 18, 2024
INTERVENTIONAL
  • BIIB122
  • Rabeprazole
Healthy Volunteer
Effect of Topical PlexoZome® Levagen® Spray on Relief of Post Exercise Knee Joint Pain
RDC Clinical Pty Ltd
Phase 4
Completed Jun 18, 2024
INTERVENTIONAL
  • Placebo topical spray solution
  • PlexoZome® Levagen® topical spray solution
Knee Joint Pain
Effect of Erythromycin on the Absorption, Metabolism and Elimination of CHF6001 in Healthy Volunteers
Chiesi Farmaceutici S.p.A.
Phase 1
Completed Jun 18, 2024
INTERVENTIONAL
  • CHF6001 DPI
  • Erythromycin
Chronic Obstructive Pulmonary Disease
A Study to Assess the Safety and Efficacy of a Sunscreen on Acne-Prone Skin With Inflammatory and Non-Inflammatory Acne Vulgaris
JNTL Consumer Health (Brasil) LTDA
Phase not applicable
Completed Jun 18, 2024
INTERVENTIONAL
  • Sunscreen SPF 70
Acne Vulgaris
Safety, Tolerability and Pharmacokinetics of LNK01004 Ointment in Adults With Atopic Dermatitis.
Lynk Pharmaceuticals Co., Ltd
Phase 1
Completed Jun 18, 2024
INTERVENTIONAL
  • LNK01004 ointment 0.3%
  • LNK01004 ointment 1.0%
  • LNK01004 ointment 1.5%
  • Vehicle BID
Atopic Dermatitis
Phase 1 Study of HT-102 Administered Subcustaneously in Healthy Participants and Patients with Chronic Hepatitis B for Safety, Tolerability, Pharmacokinetics (PK), and Antiviral Activity (only in Participants with Chronic HBV Infection)
Suzhou HepaThera Biotech Co., Ltd.
Phase 1
Completed Jun 18, 2024
INTERVENTIONAL
  • HT-102
  • Placebo
Chronic Hepatitis B
The PROMISE Study: Duavee in Women With DCIS
Phase 2
Completed Jun 19, 2024
INTERVENTIONAL
  • Conjugated Estrogens/Bazedoxifene
  • Laboratory Biomarker Analysis
  • Pharmacological Study
  • Placebo
  • Quality-of-Life Assessment
  • Questionnaire Administration
Ductal Breast Carcinoma In Situ Postmenopausal
Study of Bone Growth in the Sacroiliac Joint After Minimally Invasive Surgery With Titanium Implants
SI-BONE, Inc.
Phase not applicable
Completed Jun 19, 2024
INTERVENTIONAL
  • SIJ fusion with iFuse-3D
Sacroiliac Dysfunction
Clinical Study Comparing Two Models of a Travoprost Intraocular Implant
Glaukos Corporation
Phase 3
Completed Jun 19, 2024
INTERVENTIONAL
  • G2-TR intraocular implant containing travoprost
  • Sham surgery + active-comparator eye drops
Glaucoma, Open-Angle Ocular Hypertension
Clinical Study Comparing Two Models of a Travoprost Intraocular Implant
Glaukos Corporation
Phase 3
Completed Jun 19, 2024
INTERVENTIONAL
  • G2-TR intraocular implant containing travoprost
  • Sham surgery + active-comparator eye drops
Glaucoma, Open-Angle Ocular Hypertension
An Open, Study to Assess the Safety of RGTA® (OTR4132) in Patients With Acute Ischemic Stroke (AIS)
Euraxi Pharma
Phase not applicable
Completed Jun 19, 2024
INTERVENTIONAL
  • OTR4132MD
Stroke, Acute
An Open, Study to Assess the Safety of RGTA® (OTR4132) in Patients With Acute Ischemic Stroke (AIS)
Organ, Tissue, Regeneration, Repair and Replacement
Phase not applicable
Completed Jun 19, 2024
INTERVENTIONAL
  • OTR4132MD
Stroke, Acute
Etrasimod Versus Placebo for the Treatment of Moderately Active Ulcerative Colitis
Arena is a wholly owned subsidiary of Pfizer
Phase 2
Completed Jun 19, 2024
INTERVENTIONAL
  • Etrasimod
  • Placebo
Ulcerative Colitis
Etrasimod Versus Placebo for the Treatment of Moderately Active Ulcerative Colitis
Phase 2
Completed Jun 19, 2024
INTERVENTIONAL
  • Etrasimod
  • Placebo
Ulcerative Colitis
Safety and Pharmacokinetics of Fluzoparib in Healthy Subjects and Those With Impaired Liver Function
Jiangsu HengRui Medicine Co., Ltd.
Phase 1
Completed Jun 19, 2024
INTERVENTIONAL
  • Fluzoparib
Healthy Subjects Hepatic Impairment
A Study of Trastuzumab Emtansine in Combination With Atezolizumab or Placebo as a Treatment for Participants With Human Epidermal Growth Factor 2 (HER2)-Positive and Programmed Death-ligand 1 (PD-L1)-Positive Locally Advanced (LABC) or Metastatic Breast Cancer (MBC)
Hoffmann-La Roche
Phase 3
Completed Jun 19, 2024
INTERVENTIONAL
  • Atezolizumab
  • Placebo
  • Trastuzumab Emtansine
Metastatic Breast Cancer
PF-07284892 in Participants With Advanced Solid Tumors
Phase 1
Completed Jun 19, 2024
INTERVENTIONAL
  • PF-07284892
  • binimetinib
  • cetuximab
  • encorafenib
  • lorlatinib
Solid Tumor
Efficacy and Safety Study of Orvepitant for Chronic Cough in Patients With Idiopathic Pulmonary Fibrosis
Nerre Therapeutics Ltd.
Phase 2
Completed Jun 19, 2024
INTERVENTIONAL
  • Orvepitant Maleate
  • Placebo
Cough Idiopathic Pulmonary Fibrosis
Efficacy and Safety Study of Orvepitant for Chronic Cough in Patients With Idiopathic Pulmonary Fibrosis
Pharm-Olam International
Phase 2
Completed Jun 19, 2024
INTERVENTIONAL
  • Orvepitant Maleate
  • Placebo
Cough Idiopathic Pulmonary Fibrosis
Efficacy, Safety and Pharmacokinetics Study of CPL500036 (PDE10A Inhibitor) in Patients With Schizophrenia
Celon Pharma SA
Phase 2
Completed Jun 19, 2024
INTERVENTIONAL
  • CPL500036 - high dose
  • CPL500036 - low dose
  • Placebo
Schizophrenia
Phase 3 Safety and Efficacy Study of CTAP101 Extended-release Capsules in Children With Secondary Hyperparathyroidism
OPKO Health, Inc.
Phase 3
Completed Jun 19, 2024
INTERVENTIONAL
  • CTAP101
  • Placebo
Chronic Kidney Disease stage3 Chronic Kidney Disease stage4 Secondary Hyperparathyroidism Vitamin d Deficiency
A Study to Evaluate the Effects of Cenicriviroc Mesylate on Arterial Inflammation in People Living With HIV
Phase 2
Completed Jun 19, 2024
INTERVENTIONAL
  • CVC 150 mg
  • CVC 300 mg
  • Placebo for CVC 150 mg
  • Placebo for CVC 300 mg
HIV-1-infection
A Study to Investigate Different Formulations of S-337395 in Healthy Adult Participants
Shionogi
Phase 1
Completed Jun 19, 2024
INTERVENTIONAL
  • Placebo
  • S-337395
Healthy Volunteers
A Study to Evaluate the Relative Bioavailability and Food Effect of a New Tablet Formulation and Strength of Suzetrigine
Vertex Pharmaceuticals Incorporated
Phase 1
Completed Jun 19, 2024
INTERVENTIONAL
  • Suzetrigine
Pain
High Dose Cytarabine Followed by Pembrolizumab in Relapsed/Refractory AML
Merck Sharp & Dohme LLC
Phase 2
Completed Jun 20, 2024
INTERVENTIONAL
  • pembrolizumab,
Acute Myeloid Leukemia, in Relapse
Trial to Assess Safety and Efficacy of Lenvatinib (18 mg vs. 14 mg) in Combination With Everolimus in Participants With Renal Cell Carcinoma
Eisai Inc.
Phase 2
Completed Jun 20, 2024
INTERVENTIONAL
  • everolimus
  • lenvatinib
Renal Cell Carcinoma
Trial to Assess Safety and Efficacy of Lenvatinib (18 mg vs. 14 mg) in Combination With Everolimus in Participants With Renal Cell Carcinoma
Merck Sharp & Dohme LLC
Phase 2
Completed Jun 20, 2024
INTERVENTIONAL
  • everolimus
  • lenvatinib
Renal Cell Carcinoma
Lumbar Belt Benefit Compared to the Usual Care in the Treatment of Non-specific Low Back Pain
Phase not applicable
Completed Jun 20, 2024
INTERVENTIONAL
  • LombaStab belt
Low Back Pain
Lumbar Belt Benefit Compared to the Usual Care in the Treatment of Non-specific Low Back Pain
Thuasne
Phase not applicable
Completed Jun 20, 2024
INTERVENTIONAL
  • LombaStab belt
Low Back Pain
Mitoxantrone Hydrochloride Liposome Injection, Bortezomib and Dexamethasone in the Treatment of R/R MM
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.
Recruiting Phase 1
Past estimated: Jun 20, 2024
INTERVENTIONAL
  • Bortezomib for Injection
  • Dexamethasone Acetate Tablets
  • Mitoxantrone Hydrochloride Liposome injection
Relapsed or Refractory Multiple Myeloma
A Study of Chinese Adults With Lymphoma
Phase not applicable
Completed Jun 20, 2024
No interventions listed
Lymphoma
Evaluation of MoodRing on Improving the Quality of Depression Management in Adolescents
NuRelm, Inc.
Phase not applicable
Completed Jun 20, 2024
INTERVENTIONAL
  • MoodRing App
  • Usual Care
Depression in Adolescence
A Study to Evaluate the Pharmacodynamic, Efficacy and Safety of SHR-1703 in Asthma Patients With Eosinophil Phenotype
Jiangsu HengRui Medicine Co., Ltd.
Active Phase 2
Past estimated: Jun 20, 2024
INTERVENTIONAL
  • SHR-1703
  • SHR-1703 Placebo
Asthma With Eosinophilic Phenotype
A Pre-market, Multi-center, International, Double-blind, Randomized, Two-arms, Controlled, Prospective Clinical Investigation Assessing the Safety and Performance of a Medical Device (ClearPlasma™) for the Treatment of Patients Undergoing Coronary Artery Bypass or Valve Replacement
PlasFree Ltd.
Phase not applicable
Past estimated: Jun 20, 2024
INTERVENTIONAL
  • ClearPlasma
Bleeding Bypass Complication Valve Replacement
Efficacy and Safety of Inclisiran as Monotherapy in Patients With Primary Hypercholesterolemia Not Receiving Lipid-lowering Therapy.
Novartis Pharmaceuticals
Phase 3
Completed Jun 20, 2024
INTERVENTIONAL
  • Ezetimibe
  • Inclisiran
  • Matching Placebo for Ezetimibe
  • Matching Placebo for Inclisiran
Hypercholesterolemia
[14 C] Study on Mass Balance of TY-9591 in Healthy Chinese Subjects
TYK Medicines, Inc
Phase 1
Completed Jun 20, 2024
INTERVENTIONAL
  • TY-9591
Healthy Volunteers
SWC for Treatment of Superficial Partial-Thickness Burns
Synedgen, Inc.
Phase not applicable
Completed Jun 20, 2024
INTERVENTIONAL
  • SILVADENE Cream 1% (silver sulfadiazine)
  • SynePure Wound Cleanser and Catasyn Advanced Technology Hydrogel
Burn Wounds
Feasibility Study for Instant Cardiac Diagnostic and Post-operative Risk Assessment with the LynxPatch Device
Lynx Health Science GmbH
Phase not applicable
Completed Jun 20, 2024
OBSERVATIONAL
  • LynxPatch
Cardiovascular Diseases Heart Diseases
Feasibility Study for Instant Cardiac Diagnostic and Post-operative Risk Assessment with the LynxPatch Device
Meditrial Europe Ltd.
Phase not applicable
Completed Jun 20, 2024
OBSERVATIONAL
  • LynxPatch
Cardiovascular Diseases Heart Diseases
A Study of EDG-7500 in Healthy Adults
Edgewise Therapeutics, Inc.
Phase 1
Completed Jun 20, 2024
INTERVENTIONAL
  • EDG-7500
  • Placebo
Healthy Subjects
EX-PRESS® P-50 and EX-PRESS® P-200
Alcon Research
Phase not applicable
Completed Jun 20, 2024
OBSERVATIONAL
  • EX-PRESS P-200 filtration device
  • EX-PRESS P-50 filtration device
Glaucoma
AIMIGo 12L ECG Synthesis Software Pivotal Study for Arrythmia Detection
HeartBeam, Inc.
Phase not applicable
Completed Jun 20, 2024
INTERVENTIONAL
  • Vectorcardiography (VECG)
Arrhythmias, Cardiac Atrial Fibrillation Atrial Flutter Bradycardia Tachycardia
Treatment of Adults With Acute Bronchitis in the Primary Healthcare Setting
Neopharm Bulgaria Ltd.
Phase not applicable
Completed Jun 20, 2024
INTERVENTIONAL
  • Atusin CAP
  • Placebo
Acute Bronchitis
Clinical Study to Evaluate the Anti-sensitivity Efficacy of a Stannous Fluoride Toothpaste in a Population of Dentin Hypersensitivity Sufferers
Phase not applicable
Completed Jun 20, 2024
INTERVENTIONAL
  • Crest cavity protection toothpaste
  • Stannous fluoride toothpaste
Dentin Sensitivity
A Trial to Evaluate the Effect of Esomeprazole on the Pharmacokinetics of Emraclidine in Healthy Adult Participants
Cerevel Therapeutics, LLC
Phase 1
Completed Jun 20, 2024
INTERVENTIONAL
  • Emraclidine
  • Esomeprazole
Healthy Participants
A Study to Evaluate the Safety and Efficacy of DSFNC1 Soft Hydrophilic Contact Lenses and SiHy Color Soft Hydrophilic Contact Lenses
BenQ Materials Corporation
Phase not applicable
Completed Jun 20, 2024
INTERVENTIONAL
  • BenQ Materials DSFNC1 soft hydrophilic contact lenses
  • Visco SiHy Color soft hydrophilic contact lenses
Myopia
A Clinical Trial to Investigate the Safety and Efficacy of D-Mannose on Symptoms of Urinary Tract Infection in Women
KEB Nutraceuticals USA, Inc.
Phase 2
Completed Jun 20, 2024
INTERVENTIONAL
  • Placebo
  • UClear
Urinary Tract Infection(UTI)
A Clinical Trial to Investigate the Safety and Efficacy of D-Mannose on Symptoms of Urinary Tract Infection in Women
KGK Science Inc.
Phase 2
Completed Jun 20, 2024
INTERVENTIONAL
  • Placebo
  • UClear
Urinary Tract Infection(UTI)
Study of SAL-0951 Compared to Recombinant Human Erythropoietin in Anemic Patients Receiving Maintenance Hemodialysis
Shenzhen Salubris Pharmaceuticals Co., Ltd.
Phase 3
Completed Jun 20, 2024
INTERVENTIONAL
  • SAL-0951 tablets
  • rHuEPO injection
Anemia
A Study of the Effectiveness and Safety of Nivolumab Compared to Bevacizumab and of Nivolumab With or Without Ipilimumab in Glioblastoma Patients
Bristol-Myers Squibb
Phase 3
Completed Jun 21, 2024
INTERVENTIONAL
  • Bevacizumab
  • Ipilimumab
  • Nivolumab
Recurrent Glioblastoma
A Trial to Evaluate the Efficacy and Safety of Tafasitamab With Bendamustine (BEN) Versus Rituximab (RTX) With BEN in Adult Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)
Incyte Corporation
Phase 2 / Phase 3
Completed Jun 21, 2024
INTERVENTIONAL
  • Bendamustine (BEN)
  • Rituximab (RTX)
  • Tafasitamab
Diffuse Large B-cell Lymphoma
Neoadjuvant Durvalumab and Tremelimumab Plus Radiation for High Risk Soft-Tissue Sarcoma
AstraZeneca
Phase 1 / Phase 2
Completed Jun 21, 2024
INTERVENTIONAL
  • Combination Radiation, Immunotherapy, Surgery
Soft Tissue Sarcoma
A Phase 1/2 Study of FS118 in Patients With Advanced Malignancies
invoX Pharma Limited
Phase 1 / Phase 2
Completed Jun 21, 2024
INTERVENTIONAL
  • FS118
  • Paclitaxel
Advanced Cancer Metastatic Cancer Squamous Cell Carcinoma of Head and Neck
Mepolizumab for COPD Hospital Eosinophilic Admissions Pragmatic Trial
GlaxoSmithKline
Phase 2 / Phase 3
Completed Jun 21, 2024
INTERVENTIONAL
  • Mepolizumab
  • Placebo
COPD Eosinophilia
Efficacy and Safety of IBI310 Combined with Sintilimab in Patients with Advanced Hepatocellular Carcinoma
Innovent Biologics (Suzhou) Co. Ltd.
Phase 1
Completed Jun 21, 2024
INTERVENTIONAL
  • IBI308 200mg
Advanced Hepatocellular Carcinoma
LUMINOS-101: Lerapolturev (PVSRIPO) and Pembrolizumab in Patients With Recurrent Glioblastoma
Istari Oncology, Inc.
Phase 2
Completed Jun 21, 2024
INTERVENTIONAL
  • lerapolturev
  • pembrolizumab
Brain Tumor Glioblastoma Recurrent Glioblastoma Supratentorial Glioblastoma
Efficacy and Safety of MK-8189 in Participants With an Acute Episode of Schizophrenia (MK-8189-008)
Merck Sharp & Dohme LLC
Phase 2
Completed Jun 21, 2024
INTERVENTIONAL
  • MK-8189
  • Placebo to MK-8189
  • Placebo to risperidone
  • Risperidone
Schizophrenia
Autonomous Robotics for Transcatheter Cardiac Procedures
Artiness SRL
Phase not applicable
Completed Jun 21, 2024
OBSERVATIONAL
  • Percutaneous cardiac procedure
Heart Valve Diseases Mitral Valve Disease Structural Heart Abnormality
Specified Drug-use Survey on Abilify Prolonged Release Aqueous Suspension for IM Injection (Prevention of Relapse of Mood Episodes in BP)
Otsuka Pharmaceutical Co., Ltd.
Phase not applicable
Completed Jun 21, 2024
OBSERVATIONAL
  • Abilify prolonged release aqueous suspension for IM injection (Aripiprazole)
Bipolar Disorder I
Study of ASP7517 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors Expressing WT1 Antigen
Astellas Pharma Global Development, Inc.
Phase 1 / Phase 2
Completed Jun 21, 2024
INTERVENTIONAL
  • ASP7517
  • Pembrolizumab
Advanced Cancer Advanced Malignancies
Radiotherapy in Combination With Atezolizumab Prior to Surgical Resection for HPV Unrelated HNSCC
Genentech, Inc.
Phase 1
Completed Jun 21, 2024
INTERVENTIONAL
  • Atezolizumab
  • Stereotactic Body Radiation Therapy
Squamous Cell Carcinoma of Head and Neck
A 12-Week Crossover Study to Assess the Efficacy, Safety and Tolerability of L1-79 in Subjects Aged 12-21 Years With Autism Spectrum Disorder
Yamo Pharmaceuticals LLC
Phase 2
Completed Jun 21, 2024
INTERVENTIONAL
  • L1-79
Autism Autism Spectrum Disorder
Evaluation of the MiniMed™ 780G System in Type 1 Adult and Pediatric Subjects Utilizing Insulin Fiasp®
Medtronic Diabetes
Phase not applicable
Completed Jun 21, 2024
INTERVENTIONAL
  • MiniMed 780G System
Type 1 Diabetes
Validation Study of a Patch-based PSG System
Onera BV
Phase not applicable
Past estimated: Jun 21, 2024
INTERVENTIONAL
  • Polysomnography
Sleep Disorder
Doxil/Caelyx BE Study
Baxter Healthcare Corporation
Phase 1
Completed Jun 21, 2024
INTERVENTIONAL
  • DOXIL/CAELYX
AIDS-related Kaposi Sarcoma Metastatic Breast Cancer Multiple Myeloma Ovarian Cancer
Study of StimRouter for Chronic Knee OA Pain
Bioventus LLC
Phase not applicable
Completed Jun 21, 2024
OBSERVATIONAL
  • StimRouter Neuromodulation System
Osteoarthritis, Knee
Super Saturated Oxygen (SSO2) Therapy in Patients With ST-segment Elevation Myocardial Infarction (STEMI) and Action on Coronary Microcirculation Dysfunction
Zoll Medical Corporation
Not yet recruiting Phase not applicable
Past estimated: Jun 21, 2024
INTERVENTIONAL
  • SSO2 therapy
Coronary Microvascular Dysfunction STEMI
Phase 2 Study to Evaluate RPT193 in Adults With Moderate to Severe T2-high Asthma
RAPT Therapeutics, Inc.
Phase 2
Completed Jun 21, 2024
INTERVENTIONAL
  • Placebo
  • RPT193
Asthma
A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of AK120 in Subjects With Atopic Dermatitis
Phase 1 / Phase 2
Completed Jun 21, 2024
INTERVENTIONAL
  • AK120
  • Placebo
Atopic Dermatitis
Pilot Randomized Study of RD-X19 Tx Device in Subjects With PCC (Long Covid) in the Outpatient Setting
EmitBio Inc.
Phase not applicable
Completed Jun 21, 2024
INTERVENTIONAL
  • RDX-19
Post COVID-19 Condition (PCC)
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of K-757 and K-833 in Overweight/Obese Patients With Type 2 Diabetes
Kallyope Inc.
Phase 1
Completed Jun 21, 2024
INTERVENTIONAL
  • K-757 and K-833 BID
  • K-757 and K-833 QD
  • Matching placebo to K-757 and K-833 BID
  • Matching placebo to K-757 and K-833 QD
Obesity Type 2 Diabetes Mellitus (T2DM)
To Compare the Safety and PK/ PD Characteristics of ADC189 Between Hepatic Impairment and Normal Hepatic Function Subjects
Jiaxing AnDiCon Biotech Co.,Ltd
Phase 1
Completed Jun 21, 2024
INTERVENTIONAL
  • ADC189
Influenza Type A Influenza Type B
A Study to Evaluate the Drug-Drug Interaction Between Enlicitide Decanoate (MK-0616) and Alendronate in Healthy Adult Participants (MK-0616-027)
Merck Sharp & Dohme LLC
Phase 1
Completed Jun 21, 2024
INTERVENTIONAL
  • Alendronate
  • Enlicitide Decanoate
Healthy
Evaluating the Effectiveness of a Digital Therapeutic (Reviga) for People With Stress or Burnout
Gaia AG
Phase not applicable
Completed Jun 22, 2024
INTERVENTIONAL
  • reviga
Burnout Stress
Diagnosis, Antibiotic Prescribing Practices and Outcomes of cUTI in an Outpatient Setting
Pathnostics
Phase not applicable
Past estimated: Jun 23, 2024
No interventions listed
Urinary Tract Infections
A Clinical Study to Evaluate the Anti-Sensitivity Efficacy of a Stannous Fluoride Toothpaste in a Population of Dentin Hypersensitivity Sufferers
Phase not applicable
Completed Jun 23, 2024
INTERVENTIONAL
  • Regular fluoride toothpaste (Crest Cavity Protection)
  • Stannous fluoride toothpaste
Dentin Sensitivity
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of (PEG)-BHD1028
EncuraGen, Inc
Phase 1
Completed Jun 23, 2024
INTERVENTIONAL
  • (PEG)-BHD1028 Multiple Ascending Dose
  • (PEG)-BHD1028 Single Ascending Dose
  • Placebo
Insulin Resistance
A Study of MK-8507 and Islatravir (MK-8591) in Healthy Adult Participants (MK-8507-016)
Merck Sharp & Dohme LLC
Phase 1
Completed Jun 23, 2024
INTERVENTIONAL
  • Islatravir
  • MK-8507
Healthy
A Study of the Bruton's Tyrosine Kinase Inhibitor Ibrutinib Given in Combination With Bendamustine and Rituximab in Patients With Newly Diagnosed Mantle Cell Lymphoma
Janssen Research & Development, LLC
Phase 3
Completed Jun 24, 2024
INTERVENTIONAL
  • Bendamustine
  • Ibrutinib
  • Placebo
  • Rituximab
Mantle Cell Lymphoma
A Study of the Bruton's Tyrosine Kinase Inhibitor Ibrutinib Given in Combination With Bendamustine and Rituximab in Patients With Newly Diagnosed Mantle Cell Lymphoma
Pharmacyclics LLC.
Phase 3
Completed Jun 24, 2024
INTERVENTIONAL
  • Bendamustine
  • Ibrutinib
  • Placebo
  • Rituximab
Mantle Cell Lymphoma
Atezolizumab in Combination With Entinostat and Bevacizumab in Patients With Advanced Renal Cell Carcinoma
Genentech, Inc.
Phase 1 / Phase 2
Completed Jun 24, 2024
INTERVENTIONAL
  • Atezolizumab
  • Bevacizumab
  • Entinostat
Metastatic Cancer Renal Cancer
Atezolizumab in Combination With Entinostat and Bevacizumab in Patients With Advanced Renal Cell Carcinoma
Syndax Pharmaceuticals
Phase 1 / Phase 2
Completed Jun 24, 2024
INTERVENTIONAL
  • Atezolizumab
  • Bevacizumab
  • Entinostat
Metastatic Cancer Renal Cancer
Oral STAT3 Inhibitor, TTI-101, in Patients with Advanced Cancers
Tvardi Therapeutics, Incorporated
Phase 1
Completed Jun 24, 2024
INTERVENTIONAL
  • TTI-101
Advanced Cancer Breast Cancer Colorectal Cancer Gastric Adenocarcinoma Head and Neck Squamous Cell Carcinoma Hepatocellular Cancer Melanoma Non Small Cell Lung Cancer
Study to Assess AFM24 in Advanced Solid Cancers
Affimed GmbH
Phase 1 / Phase 2
Completed Jun 24, 2024
INTERVENTIONAL
  • 14 mg AFM24
  • 160 mg AFM24
  • 320 mg AFM24
  • 40 mg AFM24
  • 480 mg AFM24
  • 720 mg AFM24
  • 80 mg AFM24
Advanced Solid Tumor
Hemiverse Shoulder Prosthesis
41Hemiverse AG
Phase not applicable
Completed Jun 24, 2024
INTERVENTIONAL
  • Device: Hemiverse
Hemiarthroplasty Rotator Cuff Tears
A Study of AMG 340 in Subjects With Metastatic Castrate-Resistant Prostate Carcinoma
Phase 1
Completed Jun 24, 2024
INTERVENTIONAL
  • AMG 340
Metastatic Castration-resistant Prostate Cancer
A Safety and Efficacy Study of Anti-inflammatory (Canakinumab) and Cartilage Stimulating (LNA043) Drugs Injected Into the Knee Joint of Participants With Knee Osteoarthritis (OA)
Novartis Pharmaceuticals
Phase 2
Completed Jun 24, 2024
INTERVENTIONAL
  • LNA043
  • Placebo to canakinumab
  • canakinumab
Knee Osteoarthritis
Safety, Effectiveness and Quality of Life of Trastuzumab Deruxtecan in Patients with HER2+ Breast Cancer
Daiichi Sankyo France
Phase not applicable
Completed Jun 24, 2024
No interventions listed
HER2-positive Breast Cancer
Human Milk Oligosaccharides (HMOs) for Irritable Bowel Syndrome (IBS)
DSM Nutritional Products, Inc.
Phase not applicable
Completed Jun 24, 2024
INTERVENTIONAL
  • Human Milk Oligosaccharide Mix
  • Placebo
IBS - Irritable Bowel Syndrome Irritable Bowel Syndrome
A Study of Hepalatide Combined With TAF and PEG-IFN as Finite Treatment of Chronic Hepatitis B Patients
Shanghai HEP Pharmaceutical Co., Ltd.
Phase 2
Completed Jun 24, 2024
INTERVENTIONAL
  • Hepalatide
  • Pegylated Interferon alfa 2a
  • Placebo of Hepalatide
  • Tenofovir Alafenamide Tablets
Chronic Hepatitis B
A Study Testing the Superiority of CHF 1535 pMDI 800/24µg Total Daily Dose Compared to CHF 718 pMDI 800µg Total Daily Dose in Adults With Asthma on Medium or High-Dose Inhaled Corticosteroid
Chiesi Farmaceutici S.p.A.
Phase 3
Completed Jun 24, 2024
INTERVENTIONAL
  • Beclomethasone Dipropionate
  • Beclomethasone Dipropionate/Formoterol Fumarate
Asthma
POWER Study (Prospective Transbronchial Microwave + Robotic-Assisted Bronchoscopy)
Ethicon, Inc.
Phase not applicable
Completed Jun 24, 2024
INTERVENTIONAL
  • Transbronchial Microwave Ablation
Lung Neoplasms
A Study to Learn About Sickle Cell Disease In Adult Patients
Phase not applicable
Completed Jun 24, 2024
OBSERVATIONAL
  • Electronic Diary
Sickle Cell Disease
Real-world Dapagliflozin Treatment in Patients With Heart Failure in Portugal (EVOLUTION-HF)
AstraZeneca
Phase not applicable
Completed Jun 24, 2024
No interventions listed
Heart Failure
QA108 Phase II Study in Subjects With Intermediate Age-Related Macular Degeneration
Smilebiotek Zhuhai Limited
Phase 2
Completed Jun 24, 2024
INTERVENTIONAL
  • QA108 granules
  • QA108 granules placebo
Intermediate Age-Related Macular Degeneration
Satralizumab in Aneurysmal Subarachnoid Hemorrhage
Genentech, Inc.
Phase 1
Completed Jun 24, 2024
INTERVENTIONAL
  • Satralizumab
Aneurysmal Subarachnoid Hemorrhage Delayed Cerebral Ischemia
Pimavanserin for Sleep in Parkinson Disease
ACADIA Pharmaceuticals Inc.
Phase 1
Completed Jun 24, 2024
INTERVENTIONAL
  • Pimavanserin
Parkinson Disease
Study of mRNA-1010 Seasonal Influenza Vaccine in Adults
ModernaTX, Inc.
Phase 3
Completed Jun 24, 2024
INTERVENTIONAL
  • Licensed Quadrivalent Inactivated Seasonal Influenza Vaccine
  • mRNA-1010
Seasonal Influenza
Evaluation of an Herbal Extract on Sleep Parameters
Aventure AB
Phase not applicable
Completed Jun 24, 2024
INTERVENTIONAL
  • Herbal extract drink
  • Placebo
Sleep Onset Latency
A Study to Characterize the Prevalence of Overweight and Obesity Among Patients With Established Cardiovascular Disease
Novo Nordisk A/S
Phase not applicable
Completed Jun 24, 2024
OBSERVATIONAL
  • No treatment given
Obesity Overweight
INHALE-3: Afrezza® Combined With Insulin Degludec Versus Usual Care in Adults With Type 1 Diabetes
Mannkind Corporation
Phase 4
Completed Jun 24, 2024
INTERVENTIONAL
  • Afrezza
  • Basal Insulin
  • Rapid-acting Insulin Analog
  • insulin degludec
Diabetes Mellitus, Type 1
Proof of Concept Treatment Study of Orally Administered VH4004280 or VH4011499 in HIV-1 Infected Adults
ViiV Healthcare
Phase 2
Completed Jun 24, 2024
INTERVENTIONAL
  • VH4004280
  • VH4004280 Matching Placebo
  • VH4011499
  • VH4011499 Matching Placebo
HIV Infections
Wearable Auscultation Device Validation in Children
Strados Labs, Inc.
Phase not applicable
Completed Jun 24, 2024
OBSERVATIONAL
  • RESP™ Biosensor
Asthma Asthma in Children Pediatric Asthma Wheezing
A Positron-emission Tomography Study to Determine Brain Exposure of [11C]Savolitinib in Healthy Volunteers
AstraZeneca
Phase 1
Completed Jun 24, 2024
INTERVENTIONAL
  • Savolitinib
  • [11C]savolitinib
Healthy Volunteers
An Observational Study to Learn More About Vericiguat Treatment Patterns and Its Safety in People With Chronic Heart Failure With Reduced Ejection Fraction in Routine Medical Care in the United States
Phase not applicable
Completed Jun 24, 2024
OBSERVATIONAL
  • Vericiguat (Verquvo, BAY1021189)
Chronic Heart Failure With Reduced Ejection Fraction
Evaluation of the Clinical Performance of Daily Disposable Silicone Hydrogel Multifocal Toric Contact Lenses
Johnson & Johnson Vision Care, Inc.
Phase not applicable
Completed Jun 24, 2024
INTERVENTIONAL
  • JJVC Investigational Multifocal Toric Contact Lens manufactured in Senofilcon A (C3) material with UV blocker / HEV filter
Visual Acuity
A Randomized Triple-Blind Placebo-Controlled Study to Evaluate the Effects of a Supplement on Lower Urinary Tract Symptoms in Men.
Citruslabs
Phase not applicable
Completed Jun 24, 2024
INTERVENTIONAL
  • Placebo
  • ProstaThrive™ Supplement
Benign Prostatic Hyperplasia Erectile Dysfunction Lower Urinary Tract Symptoms
A Randomized Triple-Blind Placebo-Controlled Study to Evaluate the Effects of a Supplement on Lower Urinary Tract Symptoms in Men.
Optimale
Phase not applicable
Completed Jun 24, 2024
INTERVENTIONAL
  • Placebo
  • ProstaThrive™ Supplement
Benign Prostatic Hyperplasia Erectile Dysfunction Lower Urinary Tract Symptoms
A Single Group Study to Evaluate the Effects of a Probiotic Supplement on Vaginal Health.
Citruslabs
Phase not applicable
Completed Jun 24, 2024
INTERVENTIONAL
  • Good Girl Probiotics
Vaginal Health Women's Health
A Single Group Study to Evaluate the Effects of a Probiotic Supplement on Vaginal Health.
Love Wellness
Phase not applicable
Completed Jun 24, 2024
INTERVENTIONAL
  • Good Girl Probiotics
Vaginal Health Women's Health
Randomized Placebo Controlled Clinical Study of an Oral Product in Subjects With Menopausal Symptoms
Olly, PBC
Phase not applicable
Completed Jun 24, 2024
INTERVENTIONAL
  • Dietary Supplement with Proprietary Herbal Extract Blend and GABA
  • Placebo
Menopausal Symptoms
M7824 Versus Pembrolizumab as a First-line (1L) Treatment in Participants With Programmed Death-ligand 1 (PD-L1) Expressing Advanced Non-small Cell Lung Cancer (NSCLC)
EMD Serono Research & Development Institute, Inc.
Phase 3
Completed Jun 25, 2024
INTERVENTIONAL
  • M7824
  • Pembrolizumab
Non-small Cell Lung Cancer
M7824 Versus Pembrolizumab as a First-line (1L) Treatment in Participants With Programmed Death-ligand 1 (PD-L1) Expressing Advanced Non-small Cell Lung Cancer (NSCLC)
Merck KGaA, Darmstadt, Germany
Phase 3
Completed Jun 25, 2024
INTERVENTIONAL
  • M7824
  • Pembrolizumab
Non-small Cell Lung Cancer
Clinical Outcomes Associated with the Use of ViviGen® for the Treatment of Lumbar Degenerative Disc Disease
DePuy Synthes
Phase not applicable
Completed Jun 25, 2024
INTERVENTIONAL
  • Local Bone Autologous Bone Graft with DePuy Synthes Spinal pedicle screw system
  • ViviGen® Cellular Bone Matrix with DePuy Synthes Spinal Pedicle screw system
Degenerative Disc Disease Degenerative Spondylolisthesis Lumbar Disc Disease Lumbar Radiculopathy Lumbar Spinal Stenosis Lumbar Spondylolisthesis
FOCUS: A Phase I/II First in Human Study to Evaluate the Safety and Efficacy of GT005 Administered in Subjects With Dry AMD
Gyroscope Therapeutics Limited
Phase 1 / Phase 2
Completed Jun 25, 2024
INTERVENTIONAL
  • GT005
  • GT005/ Device: Orbit™ Subretinal Delivery System
Dry Age-related Macular Degeneration Eye Diseases Geographic Atrophy Macular Atrophy Macular Degeneration Retinal Degeneration Retinal Disease
FOCUS: A Phase I/II First in Human Study to Evaluate the Safety and Efficacy of GT005 Administered in Subjects With Dry AMD
Novartis Pharmaceuticals
Phase 1 / Phase 2
Completed Jun 25, 2024
INTERVENTIONAL
  • GT005
  • GT005/ Device: Orbit™ Subretinal Delivery System
Dry Age-related Macular Degeneration Eye Diseases Geographic Atrophy Macular Atrophy Macular Degeneration Retinal Degeneration Retinal Disease
A Study of Nivolumab or Placebo in Combination With Docetaxel in Men With Advanced Castration-resistant Prostate Cancer
Bristol-Myers Squibb
Phase 3
Completed Jun 25, 2024
INTERVENTIONAL
  • Docetaxel
  • Nivolumab
  • Placebo
  • Prednisone
Prostate Cancer
BAT7104 in Patients With Advanced Solid Tumours
Bio-Thera Solutions
Phase 1
Completed Jun 25, 2024
INTERVENTIONAL
  • BAT7104
Patients With Advanced Solid Tumors
BAT7104 in Patients With Advanced Solid Tumours
George Clinical Pty Ltd
Phase 1
Completed Jun 25, 2024
INTERVENTIONAL
  • BAT7104
Patients With Advanced Solid Tumors
A Study of CM310 in Patients With Chronic Rhinosinusitis With Nasal Polyposis (CROWNS-2)
Keymed Biosciences Co.Ltd
Phase 3
Completed Jun 25, 2024
INTERVENTIONAL
  • CM310
  • Placebo
Chronic Rhinosinusitis With Nasal Polyposis
BTL-785F Device for Non-invasive Reduction of Wrinkles and Overall Facial Improvement
BTL Industries Ltd.
Phase not applicable
Completed Jun 25, 2024
INTERVENTIONAL
  • BTL-785-7
Wrinkle
Clinical Research Study to Learn About the Effect and Safety of Different Doses of FE 999302 When Given as a Single Dose for Final Development of the Eggs After Ovarian Stimulation
Ferring Pharmaceuticals
Phase 2
Past estimated: Jun 25, 2024
INTERVENTIONAL
  • FE 999302
  • Novarel
  • Ovitrelle
Infertility
Treatment of Ano-perineal Fistulas Resistant to Surgical Treatment with a Gel and Plug of Wharton's Jelly
TBF Genie Tissulaire
Phase 1
Completed Jun 25, 2024
INTERVENTIONAL
  • SygeLIX-F + SygeLIX-G
Anal Fistula
SHR-2004 for the Prevention of Venous Thromboembolism in Patients Undergoing Total Knee Arthroplasty
Beijing Suncadia Pharmaceuticals Co., Ltd
Phase 2
Completed Jun 25, 2024
INTERVENTIONAL
  • Enoxaparin sodium injection
  • SHR-2004 injection
Prevention of Venous Thromboembolism After Knee Arthroplasty
Efficacy of OmegaBoost to Increase Omega-3 Levels in Healthy Individuals
Guardion Health Sciences, Inc.
Phase not applicable
Past estimated: Jun 25, 2024
INTERVENTIONAL
  • Nature Made (gummy)
  • Nature Made (soft gel)
  • OmegaBoost
Age-Related Macular Degeneration Dry Eye Syndromes Omega 3 Index
Transthyretin Amyloidosis Cardiomyopathy in Patients With HFpEF in Russia
AstraZeneca
Phase not applicable
Completed Jun 25, 2024
No interventions listed
Transthyretin Amyloidosis Cardiomyopathy, Heart Failure With Preserved Ejection Fraction
Study Aimed at Evaluation of the Effectiveness and Tolerability of an Anti-cellulite Cream Medical Device
ICIM International S.r.l.
Phase not applicable
Completed Jun 25, 2024
INTERVENTIONAL
  • Anti-cellulite cream-gel Medical Device (DEFBODY)
Cellulite
Efficacy and Safety of Probiotic Products for Digestive Health
Wecare Probiotics Co., Ltd.
Phase not applicable
Past estimated: Jun 25, 2024
INTERVENTIONAL
  • Probiotic
Healthy Adult
Clinical Experimental Study to Investigate Specific Features of ClampArt®
Profil Institut für Stoffwechselforschung GmbH
Phase not applicable
Completed Jun 26, 2024
INTERVENTIONAL
  • ClampArt
Diabetes Mellitus
A Study of Avelumab With Axitinib Versus Sunitinib In Advanced Renal Cell Cancer (JAVELIN Renal 101)
Phase 3
Completed Jun 26, 2024
INTERVENTIONAL
  • Avelumab (MSB0010718C)
  • Axitinib (AG-013736)
  • Sunitinib
Renal Cell Cancer
A Study of Avelumab With Axitinib Versus Sunitinib In Advanced Renal Cell Cancer (JAVELIN Renal 101)
Phase 3
Completed Jun 26, 2024
INTERVENTIONAL
  • Avelumab (MSB0010718C)
  • Axitinib (AG-013736)
  • Sunitinib
Renal Cell Cancer
Study of Ibrutinib Combined With Venetoclax in Subjects With Mantle Cell Lymphoma (SYMPATICO)
Janssen Research & Development, LLC
Phase 3
Completed Jun 26, 2024
INTERVENTIONAL
  • Ibrutinib
  • Placebo Oral tablet to match Venetoclax
  • Venetoclax
Mantle-Cell Lymphoma
Study of Ibrutinib Combined With Venetoclax in Subjects With Mantle Cell Lymphoma (SYMPATICO)
Pharmacyclics LLC.
Phase 3
Completed Jun 26, 2024
INTERVENTIONAL
  • Ibrutinib
  • Placebo Oral tablet to match Venetoclax
  • Venetoclax
Mantle-Cell Lymphoma
The TransCatheter Valve and Vessels Trial
Medtronic
Phase not applicable
Completed Jun 26, 2024
INTERVENTIONAL
  • CABG and SAVR
  • FFR-guided PCI and TAVI
Aortic Stenosis CABG Fractional Flow Reserve Multi Vessel Coronary Artery Disease PCI TAVI
Safety and Tolerability of the Ophthalmic Gel PRO-165 Versus Artelac® Nightime Gel
Laboratorios Sophia S.A de C.V.
Phase 1
Completed Jun 26, 2024
INTERVENTIONAL
  • Artelac
  • PRO-165
Dry Eye Syndromes
An Open-Label and Long-Term Extension Study to Evaluate the Efficacy and Safety of Ustekinumab in the Treatment of Patients With Ichthyoses
Janssen Scientific Affairs, LLC
Phase 1
Completed Jun 26, 2024
INTERVENTIONAL
  • Ustekinumab
Ichthyosis
Asciminib in Monotherapy for Chronic Myeloid Leukemia in Chronic Phase (CML-CP) With and Without T315I Mutation
Novartis Pharmaceuticals
Phase 3
Completed Jun 26, 2024
INTERVENTIONAL
  • ABL001
Chronic Myelogenous Leukemia - Chronic Phase
Asciminib in Monotherapy for Chronic Myeloid Leukemia in Chronic Phase (CML-CP) With and Without T315I Mutation
Novartis Pharmaceuticals
Phase 3
Completed Jun 26, 2024
INTERVENTIONAL
  • ABL001
Chronic Myelogenous Leukemia - Chronic Phase
A Study of Abemaciclib (LY2835219) Plus Hormone Therapy in Participants With Early Breast Cancer
Eli Lilly and Company
Phase 3
Completed Jun 26, 2024
INTERVENTIONAL
  • Abemaciclib
  • Placebo
  • Standard Adjuvant ET
Breast Neoplasms
Buprenorphine Extended-Release Subcutaneous Injection (RBP-6000) in High-risk Users
Indivior Inc.
Phase 4
Completed Jun 26, 2024
INTERVENTIONAL
  • Extended-release Buprenorphine
  • Transmucosal Buprenorphine
Moderate to Severe Opioid-use Disorder
Natural History Study of ENPP1 Deficiency and the Early-onset Form of ABCC6 Deficiency
Inozyme Pharma
Phase not applicable
Completed Jun 26, 2024
OBSERVATIONAL
  • No Intervention for this observational study
ATP-Binding Cassette Subfamily C Member 6 Deficiency Autosomal Recessive Hypophosphatemic Rickets Ectonucleotide Pyrophosphatase/phosphodiesterase1 Deficiency Generalized Arterial Calcification of Infancy
A Study of JNJ-73763989, JNJ-64300535, and Nucleos(t)Ide Analogs in Virologically Suppressed, Hepatitis B e Antigen (HBeAg)- Negative Participants With Chronic Hepatitis B Virus Infection
Janssen Research & Development, LLC
Phase 1
Completed Jun 26, 2024
INTERVENTIONAL
  • ETV monohydrate
  • JNJ-64300535
  • JNJ-73763989
  • TAF
  • Tenofovir disoproxil
Hepatitis B, Chronic
A Study of JNJ-64281802 for the Prevention of Dengue Infection
Janssen Research & Development, LLC
Phase 2
Completed Jun 26, 2024
INTERVENTIONAL
  • JNJ-64281802
  • Placebo
Dengue
Effect of Medium Cut-Off Hemodialysis on Protein Energy Wasting: The EMCOPEW Study
Baxter Healthcare Corporation
Phase not applicable
Past estimated: Jun 26, 2024
INTERVENTIONAL
  • Hemodialysis sessions
End Stage Renal Disease (ESRD)
Study of Magrolimab Given Together With FOLFIRI/BEV in Patients With Previously Treated Advanced Inoperable Metastatic Colorectal Cancer (mCRC)
Gilead Sciences
Phase 2
Completed Jun 26, 2024
INTERVENTIONAL
  • Bevacizumab
  • Fluorouracil
  • Irinotecan
  • Leucovorin
  • Magrolimab
Metastatic Colorectal Cancer
A Human Tick Kill Study to Investigate the Safety, Tolerability, and Whole Blood Concentration of TP-05
Tarsus Pharmaceuticals, Inc.
Phase 2
Completed Jun 26, 2024
INTERVENTIONAL
  • High Dose TP-05
  • Low Dose TP-05
  • Placebo Comparator
Healthy Volunteer
A Study of PRT3645 in Participants With Select Advanced or Metastatic Solid Tumors
Prelude Therapeutics
Phase 1
Completed Jun 26, 2024
INTERVENTIONAL
  • PRT3645
Breast Cancer Endometrial Cancer Glioblastoma Head and Neck Squamous Cell Carcinoma Malignant Mesothelioma Non-small Cell Lung Cancers Sarcoma
Vascular Positioning System G4 Algorithm ECG Data Collection for Model Training Study
Teleflex
Phase not applicable
Completed Jun 26, 2024
OBSERVATIONAL
  • Digital ECG Data Collection
Peripheral ICC
A Study to Learn About a Type of Pneumococcal Vaccine With a New Ingredient (PF-07872411) Intended to Enhance the Effects of the Vaccine Which is Given to Adults
Phase 1
Completed Jun 26, 2024
INTERVENTIONAL
  • Low dose multivalent pneumococcal conjugate vaccine formulation A
  • Low dose multivalent pneumococcal conjugate vaccine formulation B
  • Low dose of multivalent pneumococcal conjugate vaccine control
  • Standard dose multivalent pneumococcal conjugate vaccine control
Pneumococcal Disease
Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ZYIL1 in Patients With Amyotrophic Lateral Sclerosis
Zydus Lifesciences Limited
Phase 2
Completed Jun 26, 2024
INTERVENTIONAL
  • Matching placebo 25 mg and Matching placebo 50 mg
  • ZYIL1 capsules 25 mg and 50 mg Placebo
  • ZYIL1 capsules 25 mg and ZYIL1 capsules 50 mg
  • ZYIL1 capsules 50 mg and 25 mg Placebo
Amyotrophic Lateral Sclerosis
Fibricheck Detection cApabilities for Atrial Fibrillation
Qompium NV
Phase not applicable
Completed Jun 26, 2024
INTERVENTIONAL
  • FibriCheck Mobile Application
Atrial Fibrillation
A Thorough QT Study of ABBV-CLS-7262 in Healthy Subjects
Phase 1
Completed Jun 26, 2024
INTERVENTIONAL
  • ABBV-CLS-7262
  • Moxifloxacin 400mg
  • Placebo
Healthy
A Thorough QT Study of ABBV-CLS-7262 in Healthy Subjects
Calico Life Sciences LLC
Phase 1
Completed Jun 26, 2024
INTERVENTIONAL
  • ABBV-CLS-7262
  • Moxifloxacin 400mg
  • Placebo
Healthy
Prevalence of DAO (diamino Oxidase) Deficiency in Newborns
AB Biotek
Phase not applicable
Completed Jun 26, 2024
No interventions listed
DAO Genetic Variants
A Study of Doxorubicin Plus Olaratumab (LY3012207) in Participants With Advanced or Metastatic Soft Tissue Sarcoma
Eli Lilly and Company
Phase 3
Completed Jun 27, 2024
INTERVENTIONAL
  • Doxorubicin
  • Olaratumab
  • Placebo
Soft Tissue Sarcoma
A Study of Anti-PD-L1 Checkpoint Antibody (LY3300054) Alone and in Combination in Participants With Advanced Refractory Solid Tumors
Eli Lilly and Company
Phase 1
Completed Jun 27, 2024
INTERVENTIONAL
  • Abemaciclib
  • LY3300054
  • LY3321367
  • Merestinib
  • Ramucirumab
Breast Cancer (HR+HER2-) Cutaneous Melanoma Microsatellite Instability-High (MSI-H) Solid Tumors Pancreatic Cancer Solid Tumor
Assessing the Clinical Benefit of Molecular Profiling in Patients With Solid Tumors
Strata Oncology
Phase not applicable
Completed Jun 27, 2024
No interventions listed
Adult Solid Tumor Cancer Lymphoma Multiple Myeloma
Sleep To Reduce Incident Depression Effectively
Big Health Inc.
Phase not applicable
Completed Jun 27, 2024
INTERVENTIONAL
  • Sleep Hygiene Education Control
  • digital Cognitive Behavioral Therapy for Insomnia
  • face-to-face Cognitive Behavioral Therapy for Insomnia
Insomnia, Primary Major Depressive Disorder Rumination
A Study of Bevacizumab, Carboplatin, and Paclitaxel or Pemetrexed With or Without Atezolizumab in Chemotherapy-Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer (IMpower151)
Hoffmann-La Roche
Phase 3
Completed Jun 27, 2024
INTERVENTIONAL
  • Atezolizumab
  • Bevacizumab
  • Carboplatin
  • Paclitaxel
  • Pemetrexed
  • Placebo
Carcinoma, Non-Small-Cell Lung
Treatment of Post-Operative Pain Following Orthopedic Surgery With SPRINT® Peripheral Nerve Stimulation (PNS) System
SPR Therapeutics, Inc.
Phase not applicable
Completed Jun 27, 2024
INTERVENTIONAL
  • SPRINT Peripheral Nerve Stimulation (PNS) System
Partial Knee Replacement Postoperative Pain Total Knee Arthroplasty Total Knee Replacement
Assessment of the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type
Otsuka Pharmaceutical Development & Commercialization, Inc.
Phase 3
Completed Jun 27, 2024
INTERVENTIONAL
  • AVP-786
  • Placebo
Agitation in Patients With Dementia of the Alzheimer's Type
Multicentric Clinical Study on Isatis TF Trifocal Intraocular Lens
Cutting Edge SAS
Phase not applicable
Completed Jun 27, 2024
INTERVENTIONAL
  • Implantation of monofocal IOL, Isatis (control device)
  • Implantation of trifocal IOL, Isatis TF (device under investigation)
Cataract Lens Opacities
Multicentric Clinical Study on Isatis TF Trifocal Intraocular Lens
targomedGmbH
Phase not applicable
Completed Jun 27, 2024
INTERVENTIONAL
  • Implantation of monofocal IOL, Isatis (control device)
  • Implantation of trifocal IOL, Isatis TF (device under investigation)
Cataract Lens Opacities
Safety and Efficacy of NTX-001 Compared to SOC in Acute Single Peripheral Nerve Injuries
Neuraptive Therapeutics Inc.
Phase 2
Completed Jun 27, 2024
INTERVENTIONAL
  • NTX-001
Peripheral Nerve Injuries
Study Comparing Two Versus Three Active MDMA-assisted Sessions in U.S. Military Veterans With Chronic PTSD
Lykos Therapeutics
Phase 2
Completed Jun 27, 2024
INTERVENTIONAL
  • Midomafetamine
  • Psychotherapy
PTSD
Clinical Use of EVUSHELD as Pre-exposure Prophylaxis in Real-world Setting in Gulf Cooperation Council Countries
AstraZeneca
Phase not applicable
Completed Jun 27, 2024
No interventions listed
COVID-19
A Study to Learn About the Study Medicine (Called Avelumab) in People With Advanced Urothelial Cancer After Chemotherapy
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Phase not applicable
Completed Jun 27, 2024
OBSERVATIONAL
  • Avelumab
Urothelial Cancer
Open-Label Extension Study of ASTORIA
Contera Pharma A/S
Phase 2
Completed Jun 27, 2024
INTERVENTIONAL
  • JM-010
Dyskinesias
Clinical Study to Evaluate the Performance of Synthetic Polyurethane Male Condoms
Okamoto Industries, Inc.
Phase not applicable
Completed Jun 27, 2024
INTERVENTIONAL
  • Condom
Performance of Synthetic Polyurethane Male Condom
A Study to Investigate the Safety, Tolerability, Immunogenicity, and Pharmacodynamics of VXX-401 Administered IM in Adult Participants
Novotech (Australia) Pty Limited
Phase 1
Past estimated: Jun 27, 2024
INTERVENTIONAL
  • Placebo
  • VXX-401
Hypercholesterolemia
A Study to Investigate the Safety, Tolerability, Immunogenicity, and Pharmacodynamics of VXX-401 Administered IM in Adult Participants
Vaxxinity, Inc.
Phase 1
Past estimated: Jun 27, 2024
INTERVENTIONAL
  • Placebo
  • VXX-401
Hypercholesterolemia
LUTATHERA Injection General Use Result Survey
Novartis Pharmaceuticals
Phase not applicable
Completed Jun 27, 2024
OBSERVATIONAL
  • LUTATHERA
Somatostatin Receptor-positive Neuroendocrine Tumor
A Study to Learn About How Loss of Liver Function Affects the Blood Levels of the Study Medicine Called PF-07817883.
Phase 1
Completed Jun 27, 2024
INTERVENTIONAL
  • PF-07817883
COVID-19
Study of Safety and Effectiveness of the Boston Orthokeratology Shaping Lens in the Arise Orthokeratology Lens
Bausch & Lomb Incorporated
Phase not applicable
Completed Jun 27, 2024
INTERVENTIONAL
  • orthokeratology lens
Astigmatism
HyBryte (Synthetic Hypericin) Versus Valchlor (Mechlorethamine) in the Treatment of CTCL
Soligenix
Phase 2
Completed Jun 27, 2024
INTERVENTIONAL
  • Hypericin
  • Mechlorethamine Topical Gel
Cutaneous T-Cell Lymphoma/Mycosis Fungoides
Older Adults Exercising On Time
Corsano Health B.V.
Phase not applicable
Completed Jun 27, 2024
INTERVENTIONAL
  • Physical activity timing
Circadian Rhythm Disorders Insomnia
Accuracy of an Echo-Stress Protocol Using Regadenoson With Speckle Tracking
Astellas Scientific & Medical Affairs, Inc.
Phase 4
Completed Jun 28, 2024
INTERVENTIONAL
  • Regadenoson
Ischemia
Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia
Phase 1
Completed Jun 28, 2024
INTERVENTIONAL
  • 6-Mercaptopurine
  • Carfilzomib
  • Cyclophosphamide
  • Cytarabine
  • Daunorubicin
  • Dexamethasone
  • Intrathecal (IT) Methotrexate
  • Intrathecal Triple Therapy (Intrathecal Cytarabine, Hydrocortisone, and Methotrexate)
  • Mitoxantrone
  • PEG-asparaginase
  • Vincristine
Acute Lymphoblastic Leukemia (ALL)
Screening Protocol for Tumor Antigen Expression Profiling and HLA Typing for Eligibility Determination
Adaptimmune
Phase not applicable
Completed Jun 28, 2024
No interventions listed
Solid and Hematological Malignancies
Long-Term Safety Study of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women
Phase 3
Completed Jun 28, 2024
INTERVENTIONAL
  • E2/NETA
  • E2/NETA Placebo
  • Elagolix
  • Elagolix Placebo
Heavy Menstrual Bleeding Uterine Fibroids
GPPAD-POInT (Global Platform of Autoimmune Diabetes - Primary Oral Insulin Trial)
Helmholtz Zentrum München
Phase 2
Completed Jun 28, 2024
INTERVENTIONAL
  • Oral Insulin
  • Placebo
Diabetes Mellitus, Type 1
A Study of INCMGA00012 in Metastatic Merkel Cell Carcinoma (POD1UM-201)
Incyte Corporation
Phase 2
Completed Jun 28, 2024
INTERVENTIONAL
  • Retifanlimab
Metastatic Merkel Cell Carcinoma
HC-1119 Versus Enzalutamide in Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Hinova Pharmaceuticals USA, Inc.
Phase 3
Completed Jun 28, 2024
INTERVENTIONAL
  • Enzalutamide
  • HC-1119
Castration-resistant Prostate Cancer Prostate Cancer Metastatic
Study of Efficacy and Safety of Erenumab in Adult Chronic Migraine Patients
Novartis Pharmaceuticals
Phase 3
Past estimated: Jun 28, 2024
INTERVENTIONAL
  • Erenumab
  • Placebo
Migraine
Basket Trial of IDX-1197, a PARP Inhibitor, in Patients with HRR Mutated Solid Tumors (VASTUS)
Idience Co., Ltd.
Phase 1 / Phase 2
Completed Jun 28, 2024
INTERVENTIONAL
  • IDX-1197
Homologous Recombination Deficiency Homologous Recombination Repair Gene Mutation Solid Tumors
NAsal Polyps: Inflammatory & Molecular Phenotyping of Responders to Benralizumab
AstraZeneca
Phase 3
Completed Jun 28, 2024
INTERVENTIONAL
  • Benralizumab
  • Placebo
Nasal Polyps
Fixed-Dose Trial in Early Parkinson's Disease (PD)
Cerevel Therapeutics, LLC
Phase 3
Completed Jun 28, 2024
INTERVENTIONAL
  • Placebo
  • Tavapadon
Parkinson Disease
Study with Afuresertib and Paclitaxel in Platinum Resistant Ovarian
Laekna Limited
Phase 2
Completed Jun 28, 2024
INTERVENTIONAL
  • Afuresertib
  • Paclitaxel
Platinum-resistant Ovarian Cancer
Study to Assess the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type
Otsuka Pharmaceutical Development & Commercialization, Inc.
Phase 3
Completed Jun 28, 2024
INTERVENTIONAL
  • AVP-786
  • Placebo
Agitation in Patients With Dementia of the Alzheimer's Type
A Study of Pembrolizumab (MK-3475) Plus Carboplatin and Paclitaxel as First-line Treatment of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (MK-3475-B10/KEYNOTE B10)
Merck Sharp & Dohme LLC
Phase 4
Completed Jun 28, 2024
INTERVENTIONAL
  • Carboplatin
  • Paclitaxel
  • Pembrolizumab
Squamous Cell Carcinoma of Head and Neck
Carcinoma of Unknown Primary (CUP): a Comparison Across Tissue and Liquid Biomarkers
Phase not applicable
Completed Jun 28, 2024
No interventions listed
Cancer of Unknown Primary Site
Carcinoma of Unknown Primary (CUP): a Comparison Across Tissue and Liquid Biomarkers
Hoffmann-La Roche
Phase not applicable
Completed Jun 28, 2024
No interventions listed
Cancer of Unknown Primary Site
Extension Study to Evaluate Safety and Efficacy of Jaktinib in Adults With Alopecia Areata
Suzhou Zelgen Biopharmaceuticals Co.,Ltd
Phase 3
Completed Jun 28, 2024
INTERVENTIONAL
  • Jaktinib
Alopecia Areata
Post Marketing Surveillance (PMS) of JARDIANCE in Chronic Heart Failure (CHF)
Boehringer Ingelheim
Phase not applicable
Completed Jun 28, 2024
OBSERVATIONAL
  • JARDIANCE®
Heart Failure
Post Marketing Surveillance (PMS) of JARDIANCE in Chronic Heart Failure (CHF)
Eli Lilly and Company
Phase not applicable
Completed Jun 28, 2024
OBSERVATIONAL
  • JARDIANCE®
Heart Failure
Data Source and Provenance

All data is sourced from the Aggregate Content of ClinicalTrials.gov, put together by the Clinical Trials Transformation Initiative (CTTI). This is a fantastic project and resource that makes the canonical data on ClinicalTrials.gov available for researchers like us. We refresh our clinical trial database with AACT data daily. This data table is a selection of the most recent 500 studies since June 2024.

Page Last Refreshed: Apr 4, 2025

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