Clinical Trial Data
Clinical Trial Change Feed
Daily-detected changes across ClinicalTrials.gov records, structured and labeled by change type. Status changes, protocol amendments, endpoint modifications, enrollment shifts, and new site additions or removals.
Request dataset →Detected this week
Recent changes caught automatically from ClinicalTrials.gov.
Updated Sep 28, 2026
A new secondary endpoint, "Absolute Change from Baseline in 24-hour Cough Frequency", was added.
Completion date: 2026-09-30 → 2026-11-30
Trial stopped: Withdrawal of the marketing authorization for the breast cancer indication of Talzenna® in Korea, not related to safety...
Detailed Change Tracking Available
Trials change quietly. We don't miss it.
Daily comparison against ClinicalTrials.gov. Endpoint modifications, enrollment shifts, and status change categorized and summarized automatically.
NCT07525206
A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer
AbbVie Inc. ABBV
Enrollment
990
Primary Completion
2029-05
Detected
Sep 15, 2026
Secondary endpoint 1 timeframe
Secondary endpoint 2 timeframe
+ 2 more endpoints modified
AI Summary
Two secondary endpoints related to EORCT QLQ-C30 domains were removed. Two new secondary endpoints were added, focusing on Overall Survival (OS) in participants with c-Met subgroups (< 10%, 3+ and >= 10%, 3+). The primary endpoints remain unchanged.
Change Detection
What gets caught.
ClinicalTrials.gov logs every update but doesn't surface them. We run a daily comparison and categorize every change.
Endpoint Modifications
Primary and secondary endpoint changes, outcome measures added or removed, assessment timepoints shifted.
Enrollment Changes
Target enrollment updated, eligibility criteria modified, new sites added, age range or inclusion/exclusion criteria changed.
Status Shifts
Recruiting, suspended, terminated, completed. Caught the day the registry updates. Stopped trials flagged immediately.
Study Arms
Arms added or dropped, dosing changes, new intervention branches, comparator updates across multi-arm studies.
Company Pipeline View
Trials organized by company.
Every company mapped to their complete trial pipeline. Trials with recent changes flagged automatically. Sample from Solid Biosciences Inc. (SLDB).
Solid Biosciences Inc. SLDB
A Study of SGT-003 Gene Therapy in Ambulant Males With Duchenne Muscular Dystrophy (IMPACT...
NCT07160634 · 80 enrolled
A Study of SGT-003 Gene Therapy in Duchenne Muscular Dystrophy (INSPIRE DUCHENNE)
NCT06138639 · 60 enrolled
A Study of SGT-212 Gene Therapy in Friedreich's Ataxia
NCT07180355 · 10 enrolled
A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (...
NCT07148089 · 18 enrolled
Use Cases
Who Uses This Data
Structured for direct analysis. No cleaning, no manual joins required.
CROs and Site Networks
- ● Monitor when competing trials open new sites in your geography
- ● Track trial status changes that signal patient pool availability or competitive pressure
- ● Identify trial activity by disease or intervention type
Pharma Business Development
- ● Track competitor pipeline changes that signal strategic pivots or program setbacks
- ● Monitor endpoint modifications as early signals of program direction
- ● Map the active trials to identify collaborators or competition in your disease or intervention area
What's Included
Delivery and Data Fields
How It's Delivered
Source cadence: Daily sync from ClinicalTrials.gov via AACT (3:30am UTC)
Primary Sources
- • ClinicalTrials.gov via AACT (NIH/NLM)
- • Registered trial records
- • Daily change detection across all registered sponsors
Fields Include
- • NCT ID and trial title
- • Change category (status, endpoint, enrollment, site, arm, date)
- • Previous and current field values
- • Change detection date
- • Sponsor name and canonical company identifier
- • Phase and MeSH condition codes
- • Reported enrollment count (before/after where applicable)
- • Primary completion and study completion dates
- • AI-generated summaries of endpoint modifications
Get the Data