Weekly Report ·

Biohedge Weekly

13D/13G filings from 18 institutional investors — cross-referenced with SEC filings, insider trades, and trial data.

69
Filings
1
Activist (13D)
8
New Positions
60
Companies

Weekly Filing Volume

13D (Activist) 13G (Passive) This week

Filings This Week

CompanyFundOwnershipType
IMMUNIC INC (IMUX)BVF Partners L.P.10.0%New 13D [SEC]
SUTRO BIOPHARMA, INC. (STRO)BVF Partners L.P.7.6%New 13G [SEC]
InspireMD, Inc. (NSPR)OrbiMed7.4%New 13G [SEC]
C4 Therapeutics, Inc. (CCCC)OrbiMed1.0% ↓4.013G/A [SEC]
Avalo Therapeutics, Inc. (AVTX)OrbiMed6.4% ↓2.513G/A [SEC]
ADC Therapeutics SA (ADCT)OrbiMed2.6% ↓1.013G/A [SEC]
CYTOMX THERAPEUTICS INC (CTMX)OrbiMed2.1% ↓3.313G/A [SEC]
Vistagen Therapeutics, Inc. (VTGN)OrbiMed4.2% ↓1.113G/A [SEC]
SI-BONE, Inc. (SIBN)OrbiMed0.0%13G/A [SEC]
INHIBIKASE THERAPEUTICS INC (IKT)Perceptive Advisors10.0%13G/A [SEC]
Opus Genetics, Inc. (IRD)Perceptive Advisors10.0%13G/A [SEC]
Celcuity Inc. (CELC)Perceptive Advisors6.8% ↑0.213G/A [SEC]
Adagio Medical (ADGM)Perceptive Advisors57.5% ↓16.113G/A [SEC]
Praxis Precision Medicines, Inc. (PRAX)Perceptive Advisors7.2% ↑0.513G/A [SEC]
TENAX THERAPEUTICS, INC. (TENX)Perceptive Advisors9.1% ↑2.113G/A [SEC]

New Positions

Funds disclosing >5% ownership in a company for the first time.

CompanyFundOwnershipType
IMMUNIC INC (IMUX)BVF Partners L.P.10.0%SC 13D [SEC]
DBV Technologies S.A. (DBVT)MPM BioImpact9.9%SC 13G [SEC]
SUTRO BIOPHARMA, INC. (STRO)BVF Partners L.P.7.6%SC 13G [SEC]
InspireMD, Inc. (NSPR)OrbiMed7.4%SC 13G [SEC]
MoonLake Immunotherapeutics (MLTX)Cormorant Asset Management, LP6.1%SC 13G [SEC]
Alkermes plc. (ALKS)Baker Brothers Advisors6.1%SC 13G [SEC]
enGene, Inc. (ENGN)Cormorant Asset Management, LP6.0%SC 13G [SEC]
CLIMB BIO INC (CLYM)MPM BioImpact5.6%SC 13G [SEC]

Multi-Fund Activity

Companies with filings from multiple institutional investors this week.

CompanyFundsNet Change
Avalo Therapeutics, Inc. (AVTX)3-2.5%
Monte Rosa Therapeutics, Inc. (GLUE)2+3.4%
ADC Therapeutics SA (ADCT)2-2.3%
Xencor Inc (XNCR)2+9.9%
TENAX THERAPEUTICS, INC. (TENX)2+12.1%
INVIVYD INC (IVVD)2+1.6%
4D Molecular Therapeutics, Inc. (FDMT)2+0.0%
INHIBIKASE THERAPEUTICS INC (IKT)2+10.0%

About This Data

Schedule 13D/13G filings are SEC disclosures that report beneficial ownership. They are required when an investor acquires more than 5% of a company's shares. Schedule 13D filings indicate activist intent (potential influence over company direction), while 13G filings indicate passive investment.

New positions are filings where a fund discloses >5% ownership in a company for the first time.

We track 18 biotech-focused institutional investors with known sector expertise.

Data from RxDataLab and the SEC.